ID   C5DFI6_LACTC            Unreviewed;       175 AA.
AC   C5DFI6;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   02-SEP-2026, entry version 78.
DE   RecName: Full=Calcineurin subunit B {ECO:0000256|ARBA:ARBA00023832};
DE   AltName: Full=Calcineurin regulatory subunit {ECO:0000256|ARBA:ARBA00031295};
DE   AltName: Full=Protein phosphatase 2B regulatory subunit {ECO:0000256|ARBA:ARBA00032848};
GN   OrderedLocusNames=KLTH0D15400g {ECO:0000313|EMBL:CAR22941.1};
OS   Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)
OS   (Yeast) (Kluyveromyces thermotolerans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Lachancea.
OX   NCBI_TaxID=559295 {ECO:0000313|EMBL:CAR22941.1, ECO:0000313|Proteomes:UP000002036};
RN   [1] {ECO:0000313|EMBL:CAR22941.1, ECO:0000313|Proteomes:UP000002036}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 56472 / CBS 6340 / NRRL Y-8284
RC   {ECO:0000313|Proteomes:UP000002036};
RX   PubMed=19525356; DOI=10.1101/gr.091546.109;
RG   The Genolevures Consortium;
RA   Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA   Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA   Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA   Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA   Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA   Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA   Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA   Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA   Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA   Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT   "Comparative genomics of protoploid Saccharomycetaceae.";
RL   Genome Res. 19:1696-1709(2009).
CC   -!- SUBUNIT: Composed of a catalytic subunit (A) and a regulatory subunit
CC       (B). {ECO:0000256|ARBA:ARBA00023792}.
CC   -!- SIMILARITY: Belongs to the calcineurin regulatory subunit family.
CC       {ECO:0000256|ARBA:ARBA00023774}.
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DR   EMBL; CU928168; CAR22941.1; -; Genomic_DNA.
DR   AlphaFoldDB; C5DFI6; -.
DR   FunCoup; C5DFI6; 880.
DR   STRING; 559295.C5DFI6; -.
DR   KEGG; lth:KLTH0D15400g; -.
DR   eggNOG; KOG0034; Eukaryota.
DR   HOGENOM; CLU_061288_10_1_1; -.
DR   InParanoid; C5DFI6; -.
DR   OMA; DTNFDRD; -.
DR   OrthoDB; 191686at2759; -.
DR   Proteomes; UP000002036; Chromosome D.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0050801; P:monoatomic ion homeostasis; IEA:UniProtKB-ARBA.
DR   CDD; cd00051; EFh; 1.
DR   FunFam; 1.10.238.10:FF:000047; Calcineurin subunit B type 1; 1.
DR   Gene3D; 1.10.238.10; EF-hand; 1.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR   InterPro; IPR002048; EF_hand_dom.
DR   PANTHER; PTHR45942; PROTEIN PHOSPATASE 3 REGULATORY SUBUNIT B ALPHA ISOFORM TYPE 1; 1.
DR   Pfam; PF13499; EF-hand_7; 2.
DR   PRINTS; PR00450; RECOVERIN.
DR   SMART; SM00054; EFh; 4.
DR   SUPFAM; SSF47473; EF-hand; 1.
DR   PROSITE; PS00018; EF_HAND_1; 4.
DR   PROSITE; PS50222; EF_HAND_2; 4.
PE   3: Inferred from homology;
KW   Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW   ProRule:PRU10142};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW   ProRule:PRU10142}; Reference proteome {ECO:0000313|Proteomes:UP000002036};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          21..56
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
FT   DOMAIN          60..88
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
FT   DOMAIN          90..125
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
FT   DOMAIN          131..166
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
SQ   SEQUENCE   175 AA;  19689 MW;  C9BD8D65A51969F3 CRC64;
     MGSGISKVMD DLLEDTNFDR DEIERLRKRF MKLDRDSSGS IDKGEFMSIP GVSSNPLAGR
     IMEVFDADNS GDVDFQEFIA GLSIFSGRGS KDDKLRFAFK IYDIDKDGYI SNGELFIVLK
     IMVGNNLEDE QLQQIVDRTI LESDKDADGK LSFEEFKNAV ETTEVANSLT LQYDI
//