ID   B9TST3_MAIZE            Unreviewed;       496 AA.
AC   B9TST3;
DT   24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   24-MAR-2009, sequence version 1.
DT   02-SEP-2026, entry version 75.
DE   RecName: Full=Glutamate decarboxylase {ECO:0000256|ARBA:ARBA00012421, ECO:0000256|RuleBase:RU361171};
DE            EC=4.1.1.15 {ECO:0000256|ARBA:ARBA00012421, ECO:0000256|RuleBase:RU361171};
GN   Name=GAD {ECO:0000313|EMBL:ABZ88153.1};
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX   NCBI_TaxID=4577 {ECO:0000313|EMBL:ABZ88153.1};
RN   [1] {ECO:0000313|EMBL:ABZ88153.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Root {ECO:0000313|EMBL:ABZ88153.1};
RA   Zhuang Y., Ren G., He C., Li X., Meng Q., Zhu C., Wang R., Zhang J.;
RT   "Cloning and Characterization of a Maize cDNA Encoding Glutamate
RT   Decarboxylase.";
RL   Plant Mol. Biol. Rep. 0:0-0(2010).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=L-glutamate + H(+) = 4-aminobutanoate + CO2;
CC         Xref=Rhea:RHEA:17785, ChEBI:CHEBI:15378, ChEBI:CHEBI:16526,
CC         ChEBI:CHEBI:29985, ChEBI:CHEBI:59888; EC=4.1.1.15;
CC         Evidence={ECO:0000256|RuleBase:RU361171};
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933,
CC         ECO:0000256|PIRSR:PIRSR602129-50, ECO:0000256|RuleBase:RU000382};
CC   -!- SIMILARITY: Belongs to the group II decarboxylase family.
CC       {ECO:0000256|ARBA:ARBA00009533, ECO:0000256|RuleBase:RU000382}.
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DR   EMBL; EU302127; ABZ88153.1; -; mRNA.
DR   AlphaFoldDB; B9TST3; -.
DR   GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-ARBA.
DR   GO; GO:0004351; F:glutamate decarboxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0006536; P:glutamate metabolic process; IEA:InterPro.
DR   CDD; cd06450; DOPA_deC_like; 1.
DR   FunFam; 3.40.640.10:FF:000022; Glutamate decarboxylase; 1.
DR   FunFam; 3.90.1150.160:FF:000001; Glutamate decarboxylase; 1.
DR   FunFam; 4.10.280.50:FF:000001; Glutamate decarboxylase; 1.
DR   Gene3D; 3.90.1150.160; -; 1.
DR   Gene3D; 4.10.280.50; -; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR010107; Glutamate_decarboxylase.
DR   InterPro; IPR002129; PyrdxlP-dep_de-COase.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   NCBIfam; TIGR01788; Glu-decarb-GAD; 1.
DR   PANTHER; PTHR43321; GLUTAMATE DECARBOXYLASE; 1.
DR   PANTHER; PTHR43321:SF37; GLUTAMATE DECARBOXYLASE; 1.
DR   Pfam; PF00282; Pyridoxal_deC; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE   2: Evidence at transcript level;
KW   Decarboxylase {ECO:0000256|ARBA:ARBA00022793,
KW   ECO:0000256|RuleBase:RU361171};
KW   Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|RuleBase:RU000382};
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW   ECO:0000256|PIRSR:PIRSR602129-50}.
FT   DOMAIN          37..381
FT                   /note="Pyridoxal phosphate-dependent decarboxylase major"
FT                   /evidence="ECO:0000259|Pfam:PF00282"
FT   MOD_RES         278
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR602129-50"
SQ   SEQUENCE   496 AA;  55839 MW;  5D2471B6314BC1E2 CRC64;
     MVLSHASSGR DDDAVASTFA SRYVRERLPR YRMPERSIPR EAAQQIISDE LMLDGNPRLN
     LASFVTTWME PECDKLIMDS INKNYVDMDE YPVTTELQNR CVNMIAHLFN APIKEDETAI
     GVGTVGSSEA IMLAGLAFKR KWQNKRKEQG KPCDRPNIVT GANVQVCWEK FARYFEVELK
     EVKLSEGYYV MDPVKAVEMV DENTICVAAI LGSTLTGEFE DVKQLNDLLT EKNKETGWDV
     PIHVDAASGG FIAPFLYPEL EWDFRLPLVK SINVSGHKYG LVYPGVGWVI WRSKEDLPEE
     LIFHINYLGT DQPTFTLNFS KGSSQIIAQY YQLIRLGFEG YRNIMQNCQE NAAILREGIA
     ATGRFDVLSK DAGVPLVAFS LRDSSRFSVF DVSENLRRFG WIVPAYTMPA DAEHVAVLRV
     VVREDFSRSL AERLVSDVRK ILRELDARAT HAVRVATATA EQSGDGVVAK KSVLEIEREV
     AARWMNAVNK KKTGVC
//