ID   B5RL32_BORDL            Unreviewed;       276 AA.
AC   B5RL32;
DT   04-NOV-2008, integrated into UniProtKB/TrEMBL.
DT   04-NOV-2008, sequence version 1.
DT   28-JAN-2026, entry version 73.
DE   RecName: Full=UTP--glucose-1-phosphate uridylyltransferase {ECO:0000256|ARBA:ARBA00019048};
DE            EC=2.7.7.9 {ECO:0000256|ARBA:ARBA00012415};
DE   AltName: Full=Alpha-D-glucosyl-1-phosphate uridylyltransferase {ECO:0000256|ARBA:ARBA00031455};
DE   AltName: Full=UDP-glucose pyrophosphorylase {ECO:0000256|ARBA:ARBA00031959};
DE   AltName: Full=Uridine diphosphoglucose pyrophosphorylase {ECO:0000256|ARBA:ARBA00032341};
GN   Name=gtaB {ECO:0000313|EMBL:ACH93161.1};
GN   OrderedLocusNames=BDU_207 {ECO:0000313|EMBL:ACH93161.1};
OS   Borrelia duttonii (strain Ly).
OC   Bacteria; Pseudomonadati; Spirochaetota; Spirochaetia; Spirochaetales;
OC   Borreliaceae; Borrelia.
OX   NCBI_TaxID=412419 {ECO:0000313|EMBL:ACH93161.1, ECO:0000313|Proteomes:UP000000611};
RN   [1] {ECO:0000313|EMBL:ACH93161.1, ECO:0000313|Proteomes:UP000000611}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ly {ECO:0000313|EMBL:ACH93161.1,
RC   ECO:0000313|Proteomes:UP000000611};
RX   PubMed=18787695; DOI=10.1371/journal.pgen.1000185;
RA   Lescot M., Audic S., Robert C., Nguyen T.T., Blanc G., Cutler S.J.,
RA   Wincker P., Couloux A., Claverie J.-M., Raoult D., Drancourt M.;
RT   "The genome of Borrelia recurrentis, the agent of deadly louse-borne
RT   relapsing fever, is a degraded subset of tick-borne Borrelia duttonii.";
RL   PLoS Genet. 4:E1000185-E1000185(2008).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=alpha-D-glucose 1-phosphate + UTP + H(+) = UDP-alpha-D-glucose
CC         + diphosphate; Xref=Rhea:RHEA:19889, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:33019, ChEBI:CHEBI:46398, ChEBI:CHEBI:58601,
CC         ChEBI:CHEBI:58885; EC=2.7.7.9;
CC         Evidence={ECO:0000256|ARBA:ARBA00048128};
CC   -!- SIMILARITY: Belongs to the UDPGP type 2 family.
CC       {ECO:0000256|ARBA:ARBA00006890}.
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DR   EMBL; CP000976; ACH93161.1; -; Genomic_DNA.
DR   RefSeq; WP_012537973.1; NC_011229.1.
DR   AlphaFoldDB; B5RL32; -.
DR   STRING; 412419.BDU_207; -.
DR   KEGG; bdu:BDU_207; -.
DR   eggNOG; COG1210; Bacteria.
DR   HOGENOM; CLU_029499_1_0_12; -.
DR   OrthoDB; 9801899at2; -.
DR   Proteomes; UP000000611; Chromosome.
DR   GO; GO:0003983; F:UTP:glucose-1-phosphate uridylyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006011; P:UDP-alpha-D-glucose metabolic process; IEA:InterPro.
DR   Gene3D; 3.90.550.10; Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A; 1.
DR   InterPro; IPR005771; GalU_uridylyltTrfase_bac/arc.
DR   InterPro; IPR005835; NTP_transferase_dom.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   PANTHER; PTHR43197; UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE; 1.
DR   PANTHER; PTHR43197:SF1; UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE; 1.
DR   Pfam; PF00483; NTP_transferase; 1.
DR   SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE   3: Inferred from homology;
KW   Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW   ECO:0000313|EMBL:ACH93161.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000611};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          2..261
FT                   /note="Nucleotidyl transferase"
FT                   /evidence="ECO:0000259|Pfam:PF00483"
SQ   SEQUENCE   276 AA;  31919 MW;  78AFC8BC926DD7C3 CRC64;
     MKGIILAAGY GTRFLPITKT IPKEMLPILN KPSIDYIIEE FINSGIKEIL IITSRRKKVL
     DNYFDREVEL EHTFIKECQK DFLEQIKLKD INICFIRQNT MMGTGHALLH AKPWIGNESV
     IVAYPDDLHI GSPPLTAQLI ELYKKTGKNI LSIIENPKNI NRYGVIELNQ DNIHVKDIVE
     KPAIGHEPSN KASIGRFLYT NEFFKFLEEG FKFHQKGEYH HIYALKKLMI ENKVLYKKIE
     GERLDIGDIE GYLETIIKIA KQDDKLLQII NNSLRN
//