ID   B4RDM4_PHEZH            Unreviewed;       310 AA.
AC   B4RDM4;
DT   23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT   23-SEP-2008, sequence version 1.
DT   02-SEP-2026, entry version 77.
DE   SubName: Full=Phosphoglycerate dehydrogenase {ECO:0000313|EMBL:ACG78414.1};
GN   OrderedLocusNames=PHZ_c2003 {ECO:0000313|EMBL:ACG78414.1};
OS   Phenylobacterium zucineum (strain HLK1).
OC   Bacteria; Pseudomonadati; Pseudomonadota; Alphaproteobacteria;
OC   Caulobacterales; Caulobacteraceae; Phenylobacterium.
OX   NCBI_TaxID=450851 {ECO:0000313|EMBL:ACG78414.1, ECO:0000313|Proteomes:UP000001868};
RN   [1] {ECO:0000313|EMBL:ACG78414.1, ECO:0000313|Proteomes:UP000001868}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HLK1 {ECO:0000313|EMBL:ACG78414.1,
RC   ECO:0000313|Proteomes:UP000001868};
RX   PubMed=18700039; DOI=10.1186/1471-2164-9-386;
RA   Luo Y., Xu X., Ding Z., Liu Z., Zhang B., Yan Z., Sun J., Hu S., Hu X.;
RT   "Complete genome of Phenylobacterium zucineum - a novel facultative
RT   intracellular bacterium isolated from human erythroleukemia cell line
RT   K562.";
RL   BMC Genomics 9:386-386(2008).
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DR   EMBL; CP000747; ACG78414.1; -; Genomic_DNA.
DR   RefSeq; WP_012522556.1; NC_011144.1.
DR   AlphaFoldDB; B4RDM4; -.
DR   STRING; 450851.PHZ_c2003; -.
DR   KEGG; pzu:PHZ_c2003; -.
DR   eggNOG; COG0111; Bacteria.
DR   HOGENOM; CLU_019796_1_0_5; -.
DR   OrthoDB; 9793626at2; -.
DR   Proteomes; UP000001868; Chromosome.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   CDD; cd12164; GDH_like_2; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR   InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43333; 2-HACID_DH_C DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR43333:SF1; D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE NAD-BINDING DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF02826; 2-Hacid_dh_C; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   NAD {ECO:0000256|ARBA:ARBA00023027};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001868}.
FT   DOMAIN          103..275
FT                   /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT                   binding"
FT                   /evidence="ECO:0000259|Pfam:PF02826"
SQ   SEQUENCE   310 AA;  33752 MW;  52487C2264201321 CRC64;
     MPNPVLLFAC HDVPAEPWLV ALQRAAPELE VRLSPEGPPE TVDFGLAWAT PPGFWNRFPR
     LRAIFSLGAG VEHLLASGAP AHVPLVRMTD PGLARDMSDF VLMRVLHYHR GMHLYLRQQE
     AQVWTPIRPP RPNGRTVGVM GLGELGAHCA RTLAEVGFRT RGWSRSAKAV EGVATFAGRD
     ELPRFLEGCE ILVCLLPLTA ETRDILDAKL FAALPQGACL IQVGRGLQLV EADLLAALDA
     GRIAAATLDV FRQEPLPQGH PFWSRADITV VPHAAAFTYP ETAAEVVAEN VRRLQAGEVP
     IGLVDRALGY
//