ID   B3RCA8_CUPTR            Unreviewed;       408 AA.
AC   B3RCA8;
DT   02-SEP-2008, integrated into UniProtKB/TrEMBL.
DT   02-SEP-2008, sequence version 1.
DT   04-NOV-2026, entry version 90.
DE   SubName: Full=Glycosyl transferase, family 2, similar to mouse Ceramide glucosyltransferase {ECO:0000313|EMBL:CAQ72533.1};
DE            EC=2.4.1.80 {ECO:0000313|EMBL:CAQ72533.1};
GN   OrderedLocusNames=RALTA_B1954 {ECO:0000313|EMBL:CAQ72533.1};
OS   Cupriavidus taiwanensis (strain DSM 17343 / BCRC 17206 / CCUG 44338 / CIP
OS   107171 / LMG 19424 / R1) (Ralstonia taiwanensis (strain LMG 19424)).
OC   Bacteria; Pseudomonadati; Pseudomonadota; Betaproteobacteria;
OC   Burkholderiales; Burkholderiaceae; Cupriavidus.
OX   NCBI_TaxID=977880 {ECO:0000313|EMBL:CAQ72533.1, ECO:0000313|Proteomes:UP000001692};
RN   [1] {ECO:0000313|EMBL:CAQ72533.1, ECO:0000313|Proteomes:UP000001692}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17343 / BCRC 17206 / CCUG 44338 / CIP 107171 / LMG 19424 /
RC   R1 {ECO:0000313|Proteomes:UP000001692};
RX   PubMed=18490699; DOI=10.1101/gr.076448.108;
RA   Amadou C., Pascal G., Mangenot S., Glew M., Bontemps C., Capela D.,
RA   Carrere S., Cruveiller S., Dossat C., Lajus A., Marchetti M., Poinsot V.,
RA   Rouy Z., Servin B., Saad M., Schenowitz C., Barbe V., Batut J., Medigue C.,
RA   Masson-Boivin C.;
RT   "Genome sequence of the beta-rhizobium Cupriavidus taiwanensis and
RT   comparative genomics of rhizobia.";
RL   Genome Res. 18:1472-1483(2008).
CC   -!- PATHWAY: Lipid metabolism; sphingolipid metabolism.
CC       {ECO:0000256|ARBA:ARBA00004760}.
CC   -!- PATHWAY: Sphingolipid metabolism. {ECO:0000256|ARBA:ARBA00004991}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; CU633750; CAQ72533.1; -; Genomic_DNA.
DR   RefSeq; WP_012356746.1; NC_010530.1.
DR   AlphaFoldDB; B3RCA8; -.
DR   GeneID; 29765033; -.
DR   KEGG; cti:RALTA_B1954; -.
DR   eggNOG; COG1215; Bacteria.
DR   HOGENOM; CLU_030898_2_0_4; -.
DR   OMA; AACVYAW; -.
DR   BioCyc; CTAI977880:RALTA_RS24965-MONOMER; -.
DR   Proteomes; UP000001692; Chromosome 2.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008120; F:ceramide glucosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006679; P:glucosylceramide biosynthetic process; IEA:TreeGrafter.
DR   CDD; cd02520; Glucosylceramide_synthase; 1.
DR   Gene3D; 3.90.550.10; Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A; 1.
DR   InterPro; IPR025993; Ceramide_glucosylTrfase.
DR   InterPro; IPR017835; Hopen-assoc_HpnI.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   NCBIfam; TIGR03472; HpnI; 1.
DR   PANTHER; PTHR12726; CERAMIDE GLUCOSYLTRANSFERASE; 1.
DR   PANTHER; PTHR12726:SF0; CERAMIDE GLUCOSYLTRANSFERASE; 1.
DR   Pfam; PF13506; Glyco_transf_21; 1.
DR   SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE   4: Predicted;
KW   Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676,
KW   ECO:0000313|EMBL:CAQ72533.1};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001692};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:CAQ72533.1};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        278..299
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          367..408
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        390..408
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   408 AA;  43472 MW;  D58FF14A9B6C7E94 CRC64;
     MAAGLAAIVP GAALVCVAAG YALAAAWLSR RGPAPRGAMA TTPVSVLKPL CGPEPRLYAN
     LATFCRQRHP CFQLVFGVRA ADDPAIAVVE RLRRDFPDCD IALVIDPQVH GSNLKVSNLI
     NLFRAARHDA LVIADSDVAV APDYLARVTA PLADAGVGVV TCLYRGHAIG GFWSRLGAQF
     IDDWFAPAVR IAHAGGSRRF AFGATIALRR DALAAIGGFE AVRDRLADDF WLGELTRQLG
     LRTVLSEVVV TTDIAEDGFT LLWQHELRWM RTIASLNPAG YAFSFVTFTW PMLALGMWLA
     PLPLVITAAA VGMIARSVLA GGAAAAWRAP LRDGLLLACW ALALAGKRVR WREQVLSVRD
     RQHSGQAPAL SPAILPQAGD GKKQAAGAAT KSSPNHATFT GIQTKRPL
//