ID   RS4_PORG3               Reviewed;         201 AA.
AC   B2RLW6;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-2008, sequence version 1.
DT   04-NOV-2026, entry version 92.
DE   RecName: Full=Small ribosomal subunit protein uS4 {ECO:0000255|HAMAP-Rule:MF_01306};
DE   AltName: Full=30S ribosomal protein S4 {ECO:0000305};
GN   Name=rpsD {ECO:0000255|HAMAP-Rule:MF_01306};
GN   OrderedLocusNames=PGN_1842;
OS   Porphyromonas gingivalis (strain ATCC 33277 / DSM 20709 / CIP 103683 / JCM
OS   12257 / NCTC 11834 / 2561).
OC   Bacteria; Pseudomonadati; Bacteroidota; Bacteroidia; Bacteroidales;
OC   Porphyromonadaceae; Porphyromonas.
OX   NCBI_TaxID=431947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33277 / DSM 20709 / CIP 103683 / JCM 12257 / NCTC 11834 /
RC   2561;
RX   PubMed=18524787; DOI=10.1093/dnares/dsn013;
RA   Naito M., Hirakawa H., Yamashita A., Ohara N., Shoji M., Yukitake H.,
RA   Nakayama K., Toh H., Yoshimura F., Kuhara S., Hattori M., Hayashi T.,
RA   Nakayama K.;
RT   "Determination of the genome sequence of Porphyromonas gingivalis strain
RT   ATCC 33277 and genomic comparison with strain W83 revealed extensive genome
RT   rearrangements in P. gingivalis.";
RL   DNA Res. 15:215-225(2008).
CC   -!- FUNCTION: One of the primary rRNA binding proteins, it binds directly
CC       to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
CC       {ECO:0000255|HAMAP-Rule:MF_01306}.
CC   -!- FUNCTION: With S5 and S12 plays an important role in translational
CC       accuracy. {ECO:0000255|HAMAP-Rule:MF_01306}.
CC   -!- SUBUNIT: Part of the 30S ribosomal subunit. Contacts protein S5. The
CC       interaction surface between S4 and S5 is involved in control of
CC       translational fidelity. {ECO:0000255|HAMAP-Rule:MF_01306}.
CC   -!- SIMILARITY: Belongs to the universal ribosomal protein uS4 family.
CC       {ECO:0000255|HAMAP-Rule:MF_01306}.
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DR   EMBL; AP009380; BAG34361.1; -; Genomic_DNA.
DR   RefSeq; WP_004583573.1; NC_010729.1.
DR   PDB; 9I5V; EM; 2.70 A; l=1-201.
DR   PDB; 9I5X; EM; 3.00 A; l=1-201.
DR   AlphaFoldDB; B2RLW6; -.
DR   EMDB; EMD-52640; -.
DR   EMDB; EMD-52641; -.
DR   SMR; B2RLW6; -.
DR   GeneID; 29256994; -.
DR   GeneID; 57239570; -.
DR   KEGG; pgn:PGN_1842; -.
DR   eggNOG; COG0522; Bacteria.
DR   HOGENOM; CLU_092403_0_2_10; -.
DR   OMA; AAFRLYY; -.
DR   OrthoDB; 9803672at2; -.
DR   BioCyc; PGIN431947:G1G2V-2056-MONOMER; -.
DR   Proteomes; UP000008842; Chromosome.
DR   GO; GO:0015935; C:small ribosomal subunit; IEA:InterPro.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0042274; P:ribosomal small subunit biogenesis; IEA:TreeGrafter.
DR   GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR   CDD; cd00165; S4; 1.
DR   FunFam; 1.10.1050.10:FF:000001; 30S ribosomal protein S4; 1.
DR   FunFam; 3.10.290.10:FF:000001; 30S ribosomal protein S4; 1.
DR   Gene3D; 1.10.1050.10; Ribosomal Protein S4 Delta 41, Chain A, domain 1; 1.
DR   Gene3D; 3.10.290.10; RNA-binding S4 domain; 1.
DR   HAMAP; MF_01306_B; Ribosomal_uS4_B; 1.
DR   InterPro; IPR022801; Ribosomal_uS4.
DR   InterPro; IPR005709; Ribosomal_uS4_bact.
DR   InterPro; IPR018079; Ribosomal_uS4_CS.
DR   InterPro; IPR001912; Ribosomal_uS4_N.
DR   InterPro; IPR002942; S4_RNA-bd.
DR   InterPro; IPR036986; S4_RNA-bd_sf.
DR   NCBIfam; NF003717; rpsD; 1.
DR   NCBIfam; TIGR01017; rpsD_bact; 1.
DR   PANTHER; PTHR11831; 30S 40S RIBOSOMAL PROTEIN; 1.
DR   PANTHER; PTHR11831:SF4; SMALL RIBOSOMAL SUBUNIT PROTEIN US4M; 1.
DR   Pfam; PF00163; Ribosomal_S4; 1.
DR   Pfam; PF01479; S4; 1.
DR   SMART; SM01390; Ribosomal_S4; 1.
DR   SMART; SM00363; S4; 1.
DR   SUPFAM; SSF55174; Alpha-L RNA-binding motif; 1.
DR   PROSITE; PS00632; RIBOSOMAL_S4; 1.
DR   PROSITE; PS50889; S4; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Reference proteome; Ribonucleoprotein; Ribosomal protein;
KW   RNA-binding; rRNA-binding.
FT   CHAIN           1..201
FT                   /note="Small ribosomal subunit protein uS4"
FT                   /id="PRO_1000140773"
FT   DOMAIN          92..154
FT                   /note="S4 RNA-binding"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01306"
FT   REGION          26..47
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   201 AA;  22927 MW;  AE85809E84C8F110 CRC64;
     MARYTGPKSK IARKFGDPIF GADKVLSKKN YPPGQHGNNR RRKTSEYGLQ LREKQKAKYT
     YGVLEKQFRH LFHRAQRAKG VTGELLIQFL EARLDNVVFR LGIAPTRSAA RQLVSHRHIT
     VDGSVVNIPS YSVKPGQVIG VRERSKSLEV IADALTGFNH SKYPWMEWDQ SSLSGKLLHM
     PDRTDIPENI KEQLIVELYS K
//