ID   B2JEM2_PARP8            Unreviewed;       235 AA.
AC   B2JEM2;
DT   10-JUN-2008, integrated into UniProtKB/TrEMBL.
DT   10-JUN-2008, sequence version 1.
DT   02-SEP-2026, entry version 78.
DE   SubName: Full=Pirin domain protein {ECO:0000313|EMBL:ACC71337.1};
GN   OrderedLocusNames=Bphy_2162 {ECO:0000313|EMBL:ACC71337.1};
OS   Paraburkholderia phymatum (strain DSM 17167 / CIP 108236 / LMG 21445 /
OS   STM815) (Burkholderia phymatum).
OC   Bacteria; Pseudomonadati; Pseudomonadota; Betaproteobacteria;
OC   Burkholderiales; Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=391038 {ECO:0000313|EMBL:ACC71337.1, ECO:0000313|Proteomes:UP000001192};
RN   [1] {ECO:0000313|Proteomes:UP000001192}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17167 / CIP 108236 / LMG 21445 / STM815
RC   {ECO:0000313|Proteomes:UP000001192};
RX   PubMed=25197461; DOI=10.4056/sigs.4861021;
RA   Moulin L., Klonowska A., Caroline B., Booth K., Vriezen J.A., Melkonian R.,
RA   James E.K., Young J.P., Bena G., Hauser L., Land M., Kyrpides N., Bruce D.,
RA   Chain P., Copeland A., Pitluck S., Woyke T., Lizotte-Waniewski M.,
RA   Bristow J., Riley M.;
RT   "Complete genome sequence of Burkholderia phymatum STM815(T), a broad host
RT   range and efficient nitrogen-fixing symbiont of Mimosa species.";
RL   Stand. Genomic Sci. 9:763-774(2014).
CC   -!- COFACTOR:
CC       Name=Fe cation; Xref=ChEBI:CHEBI:24875;
CC         Evidence={ECO:0000256|PIRSR:PIRSR006232-1};
CC       Note=Binds 1 Fe cation per subunit. {ECO:0000256|PIRSR:PIRSR006232-1};
CC   -!- SIMILARITY: Belongs to the pirin family.
CC       {ECO:0000256|ARBA:ARBA00008416, ECO:0000256|RuleBase:RU003457}.
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DR   EMBL; CP001043; ACC71337.1; -; Genomic_DNA.
DR   RefSeq; WP_012401543.1; NC_010622.1.
DR   AlphaFoldDB; B2JEM2; -.
DR   KEGG; bph:Bphy_2162; -.
DR   eggNOG; COG1741; Bacteria.
DR   HOGENOM; CLU_064194_2_2_4; -.
DR   OrthoDB; 321327at2; -.
DR   Proteomes; UP000001192; Chromosome 1.
DR   CDD; cd20311; cupin_Yhhw_C; 1.
DR   CDD; cd02910; cupin_Yhhw_N; 1.
DR   Gene3D; 2.60.120.10; Jelly Rolls; 2.
DR   InterPro; IPR012093; Pirin.
DR   InterPro; IPR003829; Pirin_N_dom.
DR   InterPro; IPR041602; Quercetinase_C.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   InterPro; IPR011051; RmlC_Cupin_sf.
DR   PANTHER; PTHR43212; QUERCETIN 2,3-DIOXYGENASE; 1.
DR   PANTHER; PTHR43212:SF3; QUERCETIN 2,3-DIOXYGENASE; 1.
DR   Pfam; PF02678; Pirin; 1.
DR   Pfam; PF17954; Pirin_C_2; 1.
DR   PIRSF; PIRSF006232; Pirin; 1.
DR   SUPFAM; SSF51182; RmlC-like cupins; 1.
PE   3: Inferred from homology;
KW   Iron {ECO:0000256|PIRSR:PIRSR006232-1};
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR006232-1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001192}.
FT   DOMAIN          9..119
FT                   /note="Pirin N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02678"
FT   DOMAIN          146..231
FT                   /note="Quercetin 2,3-dioxygenase C-terminal cupin"
FT                   /evidence="ECO:0000259|Pfam:PF17954"
FT   BINDING         57
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR006232-1"
FT   BINDING         59
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR006232-1"
FT   BINDING         101
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR006232-1"
FT   BINDING         103
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR006232-1"
SQ   SEQUENCE   235 AA;  25722 MW;  D27338B06653B3B9 CRC64;
     MIRIRRSDER GHANHGWLNA KHSFSFADYY DPEHMHFGPL RVINEDRIAA GQGFGTHGHR
     DMEIVTYVLD GALSHRDSLG NGSTIRPGDV QRMSAGTGVM HSEFNASQDD PLHLLQIWII
     PKRTGDAPGY EEKRFEDADK RGRLRVVASP EGRDGSVTIH ADASIHAGLF DGAERAEYML
     EAGRQAYVHV ARGAVTVNGE ALKAGDAAMV SDATHVTVEN GEGAEVLLFD LGQLR
//