ID   B1VSP5_STRGG            Unreviewed;       326 AA.
AC   B1VSP5;
DT   20-MAY-2008, integrated into UniProtKB/TrEMBL.
DT   20-MAY-2008, sequence version 1.
DT   02-SEP-2026, entry version 71.
DE   SubName: Full=Lipase {ECO:0000313|EMBL:BAG17599.1};
GN   OrderedLocusNames=SGR_770 {ECO:0000313|EMBL:BAG17599.1};
OS   Streptomyces griseus subsp. griseus (strain JCM 4626 / CBS 651.72 / NBRC
OS   13350 / KCC S-0626 / ISP 5235).
OC   Bacteria; Bacillati; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=455632 {ECO:0000313|EMBL:BAG17599.1, ECO:0000313|Proteomes:UP000001685};
RN   [1] {ECO:0000313|Proteomes:UP000001685}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 4626 / CBS 651.72 / NBRC 13350 / KCC S-0626 / ISP 5235
RC   {ECO:0000313|Proteomes:UP000001685};
RX   PubMed=18375553; DOI=10.1128/jb.00204-08;
RA   Ohnishi Y., Ishikawa J., Hara H., Suzuki H., Ikenoya M., Ikeda H.,
RA   Yamashita A., Hattori M., Horinouchi S.;
RT   "Genome sequence of the streptomycin-producing microorganism Streptomyces
RT   griseus IFO 13350.";
RL   J. Bacteriol. 190:4050-4060(2008).
RN   [2] {ECO:0000313|EMBL:BAG17599.1, ECO:0000313|Proteomes:UP000001685}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 4626 / CBS 651.72 / NBRC 13350 / KCC S-0626 / ISP 5235
RC   {ECO:0000313|Proteomes:UP000001685};
RA   Ohnishi Y., Ishikawa J., Hara H., Suzuki H., Ikenoya M., Ikeda H.,
RA   Yamashita A., Hattori M., Horinouchi S.;
RT   "The genome sequence of the streptomycin-producing microorganism
RT   Streptomyces griseus IFO 13350.";
RL   J. Bacteriol. 0:0-0(2008).
RN   [3] {ECO:0000313|EMBL:BAG17599.1, ECO:0000313|Proteomes:UP000001685}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 4626 / CBS 651.72 / NBRC 13350 / KCC S-0626 / ISP 5235
RC   {ECO:0000313|Proteomes:UP000001685};
RX   PubMed=18364359; DOI=10.1074/jbc.M710461200;
RA   Funabashi M., Funa N., Horinouchi S.;
RT   "Phenolic lipids synthesized by type III polyketide synthase confer
RT   penicillin resistance on Streptomyces griseus.";
RL   J. Biol. Chem. 283:13983-13991(2008).
RN   [4] {ECO:0000313|EMBL:BAG17599.1, ECO:0000313|Proteomes:UP000001685}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 4626 / CBS 651.72 / NBRC 13350 / KCC S-0626 / ISP 5235
RC   {ECO:0000313|Proteomes:UP000001685};
RA   Hirano S., Tanaka K., Ohnishi Y., Horinouchi S.;
RT   "Conditionally positive effect of the TetR-family transcriptional regulator
RT   AtrA on streptomycin production by Streptomyces griseus.";
RL   Microbiology 154:905-914(2008).
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DR   EMBL; AP009493; BAG17599.1; -; Genomic_DNA.
DR   RefSeq; WP_012378055.1; NC_010572.1.
DR   AlphaFoldDB; B1VSP5; -.
DR   KEGG; sgr:SGR_770; -.
DR   PATRIC; fig|455632.4.peg.758; -.
DR   eggNOG; COG0657; Bacteria.
DR   HOGENOM; CLU_012494_6_0_11; -.
DR   Proteomes; UP000001685; Chromosome.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR013094; AB_hydrolase_3.
DR   InterPro; IPR029058; AB_hydrolase_fold.
DR   InterPro; IPR050300; GDXG_lipolytic_enzyme.
DR   PANTHER; PTHR48081; AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C; 1.
DR   PANTHER; PTHR48081:SF8; ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR   Pfam; PF07859; Abhydrolase_3; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001685}.
FT   DOMAIN          89..297
FT                   /note="Alpha/beta hydrolase fold-3"
FT                   /evidence="ECO:0000259|Pfam:PF07859"
SQ   SEQUENCE   326 AA;  35912 MW;  6E7DF4E675523970 CRC64;
     MTDAPLPPPI TPYLEPAARA LCEATDPHPR IYEVPPEKGR EILLGLQSDE SVPRPEVDEE
     WVDVDAGQWG TVRTRVIRPK GATGPLPVVF YIHGAGWVFG DDRTHDRLFR ELTVGAGAAG
     VFPVYDRAPE AKYPTQVEQN YAVGRWVAEH GAEHGLDTSR IAVTGESVGG CMAAVFALMN
     KERGGIDLRA QVLLYPVTDA DFSTPSYLRF AEGYYLTRDG MKWFWDAYTG NIAHRSEVYA
     SPLRASLEQL RGLPTTLVIT DEADVLRDEG EKYANRLREA GVDVTSVRVA GMVHDFLLLD
     SLRDTRAANV ARGLAVDALR RALHDG
//