ID B1VLP7_STRGG Unreviewed; 1010 AA. AC B1VLP7; DT 20-MAY-2008, integrated into UniProtKB/TrEMBL. DT 20-MAY-2008, sequence version 1. DT 02-SEP-2026, entry version 93. DE SubName: Full=Secreted alpha-amylase {ECO:0000313|EMBL:BAG23438.1}; GN OrderedLocusNames=SGR_6609 {ECO:0000313|EMBL:BAG23438.1}; OS Streptomyces griseus subsp. griseus (strain JCM 4626 / CBS 651.72 / NBRC OS 13350 / KCC S-0626 / ISP 5235). OC Bacteria; Bacillati; Actinomycetota; Actinomycetes; Kitasatosporales; OC Streptomycetaceae; Streptomyces. OX NCBI_TaxID=455632 {ECO:0000313|EMBL:BAG23438.1, ECO:0000313|Proteomes:UP000001685}; RN [1] {ECO:0000313|Proteomes:UP000001685} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=JCM 4626 / CBS 651.72 / NBRC 13350 / KCC S-0626 / ISP 5235 RC {ECO:0000313|Proteomes:UP000001685}; RX PubMed=18375553; DOI=10.1128/jb.00204-08; RA Ohnishi Y., Ishikawa J., Hara H., Suzuki H., Ikenoya M., Ikeda H., RA Yamashita A., Hattori M., Horinouchi S.; RT "Genome sequence of the streptomycin-producing microorganism Streptomyces RT griseus IFO 13350."; RL J. Bacteriol. 190:4050-4060(2008). RN [2] {ECO:0000313|EMBL:BAG23438.1, ECO:0000313|Proteomes:UP000001685} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=JCM 4626 / CBS 651.72 / NBRC 13350 / KCC S-0626 / ISP 5235 RC {ECO:0000313|Proteomes:UP000001685}; RA Ohnishi Y., Ishikawa J., Hara H., Suzuki H., Ikenoya M., Ikeda H., RA Yamashita A., Hattori M., Horinouchi S.; RT "The genome sequence of the streptomycin-producing microorganism RT Streptomyces griseus IFO 13350."; RL J. Bacteriol. 0:0-0(2008). RN [3] {ECO:0000313|EMBL:BAG23438.1, ECO:0000313|Proteomes:UP000001685} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=JCM 4626 / CBS 651.72 / NBRC 13350 / KCC S-0626 / ISP 5235 RC {ECO:0000313|Proteomes:UP000001685}; RX PubMed=18364359; DOI=10.1074/jbc.M710461200; RA Funabashi M., Funa N., Horinouchi S.; RT "Phenolic lipids synthesized by type III polyketide synthase confer RT penicillin resistance on Streptomyces griseus."; RL J. Biol. Chem. 283:13983-13991(2008). RN [4] {ECO:0000313|EMBL:BAG23438.1, ECO:0000313|Proteomes:UP000001685} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=JCM 4626 / CBS 651.72 / NBRC 13350 / KCC S-0626 / ISP 5235 RC {ECO:0000313|Proteomes:UP000001685}; RA Hirano S., Tanaka K., Ohnishi Y., Horinouchi S.; RT "Conditionally positive effect of the TetR-family transcriptional regulator RT AtrA on streptomycin production by Streptomyces griseus."; RL Microbiology 154:905-914(2008). CC -!- COFACTOR: CC Name=Ca(2+); Xref=ChEBI:CHEBI:29108; CC Evidence={ECO:0000256|ARBA:ARBA00001913}; CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AP009493; BAG23438.1; -; Genomic_DNA. DR RefSeq; WP_012382069.1; NC_010572.1. DR AlphaFoldDB; B1VLP7; -. DR KEGG; sgr:SGR_6609; -. DR PATRIC; fig|455632.4.peg.6783; -. DR eggNOG; COG0366; Bacteria. DR HOGENOM; CLU_007947_0_0_11; -. DR Proteomes; UP000001685; Chromosome. DR GO; GO:2001070; F:starch binding; IEA:InterPro. DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro. DR CDD; cd11339; AmyAc_bac_CMD_like_2; 1. DR CDD; cd00063; FN3; 1. DR Gene3D; 3.20.20.80; Glycosidases; 3. DR Gene3D; 2.60.40.10; Immunoglobulins; 3. DR InterPro; IPR005085; CBM25. DR InterPro; IPR003961; FN3_dom. DR InterPro; IPR036116; FN3_sf. DR InterPro; IPR006047; GH13_cat_dom. DR InterPro; IPR017853; GH_hydrolase_sf. DR InterPro; IPR013783; Ig-like_fold. DR PANTHER; PTHR10357:SF215; ALPHA-AMYLASE 1; 1. DR PANTHER; PTHR10357; ALPHA-AMYLASE FAMILY MEMBER; 1. DR Pfam; PF00128; Alpha-amylase; 1. DR Pfam; PF03423; CBM_25; 2. DR Pfam; PF00041; fn3; 1. DR SMART; SM00642; Aamy; 1. DR SMART; SM01066; CBM_25; 2. DR SMART; SM00060; FN3; 1. DR SUPFAM; SSF51445; (Trans)glycosidases; 1. DR SUPFAM; SSF49265; Fibronectin type III; 1. DR PROSITE; PS50853; FN3; 1. PE 4: Predicted; KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023326}; KW Glycosidase {ECO:0000256|ARBA:ARBA00023295}; KW Hydrolase {ECO:0000256|ARBA:ARBA00023295}; KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}; KW Polysaccharide degradation {ECO:0000256|ARBA:ARBA00023326}; KW Reference proteome {ECO:0000313|Proteomes:UP000001685}; KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}. FT SIGNAL 1..32 FT /evidence="ECO:0000256|SAM:SignalP" FT CHAIN 33..1010 FT /evidence="ECO:0000256|SAM:SignalP" FT /id="PRO_5039152269" FT DOMAIN 264..355 FT /note="Fibronectin type-III" FT /evidence="ECO:0000259|PROSITE:PS50853" FT REGION 139..160 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 251..272 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 347..370 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 386..406 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 386..402 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 1010 AA; 108635 MW; 364988B63A8E977C CRC64; MRRTSRRLSG RPLAAAVAAA GLLGLLAAVP EAAPPSVAEP ATAPAAAAAT TATVFYSTKT RDWSAYYLHY SPDGGSWTTV PGTRMEAACA DWVKLTVPLG SAGGLKATFT DGSGTWDNNA GKNYDLGTGD ITVRDGAVAH SDPCADAGPE EPEEPPGPNS ASVYYATSTV GWSTVNLHYR PHGGAWTTVP GIGMEAACTG WVKRTVDLGT ATGLQATFNN GNGVWDNNNG NDYTLATGLT TVQDRKVTAS AKDPCAAEEP DTEAPTAPEA VKAEADGVSV LLTWEPATDD RSVTRYQVTR TGGTRGTAVT DTTSTVFSDT GLEARTAYRY TVRAVDAAGN VSAESAAASA TTGDKPPAPA AGTPLGTDPR KDPIYFVLTA RFNDGDATNN RGGSQHQKSG NAANGDPMFR GDFKGLVQKL DYVKGLGFSA LWITPVVLNR SDYDYHGYHG YDFYKVDPRL ESAGASYQDL INAAHAKGMK IYQDVVHNHS SRWGAKGLFT PKAYGVRDAQ WSWYYDEKDD AFTYDGLTVE PKSGKSYYNG DLWSTAEPSG NTCLNWGTPT GHTSPEGYRI YNCQWPNPTS GMFPKALYHN CWIGNWEGED SRSCWLHDDL ADFNTENAQV QNYLIGAYNK YIDMGVDGFR LDTAVHIPRT TWNRRFLPAI QERVTQRFGA EAAKNFFVFG EVAAFVNDKW NRGSVNHSAQ FFTWKERKEY SADDEKAALE MYDYEQQQGT GAQPVSDNAF LKGNAYHAPD RSRSSGMNII DMRMHMNFGD ADNAYHNGKD SDDATNDATY NVVYVDSHDY GPNKSSERYA GGTDAWAENM SLMWTFRGIP TLYYGSEIEF QKGKKIDCGP TCPLATTGRA YFGDHLAGEV TASDFGKVSS ATGKVADTLA APLARHLQRL NEIRRAVPAL QMGQYSTEGV SGSMAYKRRY TDAASGTDSF ALVTVSGSAT YTGVPNGTYK DAVTGDTKAV TTGTLAVPAP GKGNLRVYVL DLGGKNAAPG KIGAAGPYLK //