ID   B1P2F7_SACIS            Unreviewed;       489 AA.
AC   B1P2F7;
DT   29-APR-2008, integrated into UniProtKB/TrEMBL.
DT   29-APR-2008, sequence version 1.
DT   04-NOV-2026, entry version 62.
DE   SubName: Full=LacS {ECO:0000313|EMBL:ABY78030.1};
GN   Name=lacS {ECO:0000313|EMBL:ABY78030.1};
OS   Saccharolobus islandicus (Sulfolobus islandicus).
OC   Archaea; Thermoproteota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Saccharolobus.
OX   NCBI_TaxID=43080 {ECO:0000313|EMBL:ABY78030.1};
RN   [1] {ECO:0000313|EMBL:ABY78030.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=REN1H1 {ECO:0000313|EMBL:ABY78030.1};
RX   PubMed=18176778; DOI=10.1007/s00792-007-0125-7;
RA   Berkner S., Lipps G.;
RT   "Mutation and reversion frequencies of different Sulfolobus species and
RT   strains.";
RL   Extremophiles 12:263-270(2008).
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 1 family.
CC       {ECO:0000256|ARBA:ARBA00010838, ECO:0000256|RuleBase:RU003690}.
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DR   EMBL; EU252581; ABY78030.1; -; Genomic_DNA.
DR   RefSeq; WP_012714363.1; NZ_CP194013.1.
DR   AlphaFoldDB; B1P2F7; -.
DR   SMR; B1P2F7; -.
DR   GeneID; 15298723; -.
DR   OMA; AACDFMG; -.
DR   GO; GO:0008422; F:beta-glucosidase activity; IEA:TreeGrafter.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR053427; Beta-galactosidase.
DR   InterPro; IPR033132; GH_1_N_CS.
DR   InterPro; IPR017853; GH_hydrolase_sf.
DR   InterPro; IPR001360; Glyco_hydro_1.
DR   InterPro; IPR018120; Glyco_hydro_1_AS.
DR   NCBIfam; NF041004; Beta_gal_BgaS; 1.
DR   PANTHER; PTHR10353:SF209; GALACTOLIPID GALACTOSYLTRANSFERASE SFR2, CHLOROPLASTIC; 1.
DR   PANTHER; PTHR10353; GLYCOSYL HYDROLASE; 1.
DR   Pfam; PF00232; Glyco_hydro_1; 1.
DR   PRINTS; PR00131; GLHYDRLASE1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   PROSITE; PS00572; GLYCOSYL_HYDROL_F1_1; 1.
DR   PROSITE; PS00653; GLYCOSYL_HYDROL_F1_2; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU004468};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU004468}.
FT   ACT_SITE        387
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10055"
SQ   SEQUENCE   489 AA;  56613 MW;  6224F98B522152B5 CRC64;
     MYSFPKNFRF GWSQAGFQSE MGTPGSEDPN TDWYKWVHDP ENIAAGLVSG DLPENGPGYW
     GNYKTFHDNA QKMGLKMARL NVEWSRIFPN PLPKPQNFDE SKQDVTEVEI NQNELRRLDE
     HANKDALNHY REIFKDLKSR GIYFILNMYH WPLPSWLHDP IRVRRGDLSG PTGWLSTRTV
     YEFARFSAYI AWKFDDLVDE YSTMNEPNVV GGLGYVGVKS GFPPGYLSFE LSRKAMYNII
     QAHVRAYDGI KSVSKKPIGI IYANSSFQPL TEKDMEAVEM AEYDNRWAFF DAIIRGEIMK
     GREKVVRDDL RGRLDWIGVN YYTRTVVKKT EKGYVSLGGY GHGCERNSVS LAGLPTSDFG
     WEFFPEGLYD VLTKYWNRYH LHMYVTENGI ADDADYQRPY YLVSHVYQVH RAINSSADVR
     GYLHWSLADN YEWASGFSMR FGLLKVDYGT KRLYWRPSAL VYREIATNGG ITDEIEHLNS
     VPPIRPLRH
//