ID   B1AS24_MOUSE            Unreviewed;       145 AA.
AC   B1AS24;
DT   08-APR-2008, integrated into UniProtKB/TrEMBL.
DT   08-APR-2008, sequence version 1.
DT   02-SEP-2026, entry version 115.
DE   SubName: Full=Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta {ECO:0000313|Ensembl:ENSMUSP00000115542.2};
DE   Flags: Fragment;
GN   Name=Pik3cd {ECO:0000313|Ensembl:ENSMUSP00000115542.2,
GN   ECO:0000313|MGI:MGI:1098211};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000115542.2, ECO:0000313|Proteomes:UP000000589};
RN   [1] {ECO:0000313|Ensembl:ENSMUSP00000115542.2, ECO:0000313|Proteomes:UP000000589}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000115542.2,
RC   ECO:0000313|Proteomes:UP000000589};
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RG   Mouse Genome Sequencing Consortium;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [2] {ECO:0000313|Ensembl:ENSMUSP00000115542.2, ECO:0000313|Proteomes:UP000000589}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000115542.2,
RC   ECO:0000313|Proteomes:UP000000589};
RX   PubMed=21750661;
RA   Church D.M., Schneider V.A., Graves T., Auger K., Cunningham F., Bouk N.,
RA   Chen H.C., Agarwala R., McLaren W.M., Ritchie G.R., Albracht D.,
RA   Kremitzki M., Rock S., Kotkiewicz H., Kremitzki C., Wollam A., Trani L.,
RA   Fulton L., Fulton R., Matthews L., Whitehead S., Chow W., Torrance J.,
RA   Dunn M., Harden G., Threadgold G., Wood J., Collins J., Heath P.,
RA   Griffiths G., Pelan S., Grafham D., Eichler E.E., Weinstock G.,
RA   Mardis E.R., Wilson R.K., Howe K., Flicek P., Hubbard T.;
RT   "Modernizing reference genome assemblies.";
RL   PLoS Biol. 9:e1001091-e1001091(2011).
RN   [3] {ECO:0000313|Ensembl:ENSMUSP00000115542.2}
RP   IDENTIFICATION.
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000115542.2};
RG   Ensembl;
RL   Submitted (JAN-2026) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the PI3/PI4-kinase family. {ECO:0000256|PROSITE-
CC       ProRule:PRU00877}.
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DR   AlphaFoldDB; B1AS24; -.
DR   SMR; B1AS24; -.
DR   PeptideAtlas; B1AS24; -.
DR   ProteomicsDB; 314103; -.
DR   Antibodypedia; 4215; 603 antibodies from 42 providers.
DR   Ensembl; ENSMUST00000131224.8; ENSMUSP00000115542.2; ENSMUSG00000039936.19.
DR   AGR; MGI:1098211; -.
DR   MGI; MGI:1098211; Pik3cd.
DR   VEuPathDB; HostDB:ENSMUSG00000039936; -.
DR   GeneTree; ENSGT00940000159079; -.
DR   HOGENOM; CLU_116779_0_0_1; -.
DR   OMA; CCEPQIT; -.
DR   Proteomes; UP000000589; Chromosome 4.
DR   Bgee; ENSMUSG00000039936; Expressed in granulocyte and 170 other cell types or tissues.
DR   ExpressionAtlas; B1AS24; baseline and differential.
DR   Gene3D; 3.10.20.770; -; 1.
DR   InterPro; IPR003113; PI3K_ABD.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   Pfam; PF02192; PI3K_p85B; 1.
DR   SMART; SM00143; PI3K_p85B; 1.
DR   SUPFAM; SSF54236; Ubiquitin-like; 1.
DR   PROSITE; PS51544; PI3K_ABD; 1.
PE   1: Evidence at protein level;
KW   Proteomics identification {ECO:0007829|PeptideAtlas:B1AS24,
KW   ECO:0007829|ProteomicsDB:B1AS24};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT   DOMAIN          16..105
FT                   /note="PI3K-ABD"
FT                   /evidence="ECO:0000259|PROSITE:PS51544"
FT   NON_TER         145
FT                   /evidence="ECO:0000313|Ensembl:ENSMUSP00000115542.2"
SQ   SEQUENCE   145 AA;  16878 MW;  BF2CB69A62C85913 CRC64;
     MPPGVDCPME FWTKEESQSV VVDFLLPTGV YLNFPVSRNA NLSTIKQVLW HRAQYEPLFH
     MLSDPEAYVF TCVNQTAEQQ ELEDEQRRLC DIQPFLPVLR LVAREGDRVK KLINSQISLL
     IGKGLHEFDS LRDPEVNDFR TKMRQ
//