ID   B0TES5_HELMI            Unreviewed;       154 AA.
AC   B0TES5;
DT   08-APR-2008, integrated into UniProtKB/TrEMBL.
DT   08-APR-2008, sequence version 1.
DT   28-JAN-2026, entry version 74.
DE   RecName: Full=Pyruvoyl-dependent arginine decarboxylase AaxB {ECO:0000256|ARBA:ARBA00014727};
DE            EC=4.1.1.19 {ECO:0000256|ARBA:ARBA00012426};
GN   Name=pdaD {ECO:0000313|EMBL:ABZ84327.1};
GN   ORFNames=HM1_1757 {ECO:0000313|EMBL:ABZ84327.1};
OS   Heliobacterium modesticaldum (strain ATCC 51547 / Ice1).
OC   Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales;
OC   Heliobacteriaceae; Heliomicrobium.
OX   NCBI_TaxID=498761 {ECO:0000313|EMBL:ABZ84327.1, ECO:0000313|Proteomes:UP000008550};
RN   [1] {ECO:0000313|EMBL:ABZ84327.1, ECO:0000313|Proteomes:UP000008550}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51547 / Ice1 {ECO:0000313|Proteomes:UP000008550};
RX   PubMed=18441057; DOI=10.1128/JB.00299-08;
RA   Sattley W.M., Madigan M.T., Swingley W.D., Cheung P.C., Clocksin K.M.,
RA   Conrad A.L., Dejesa L.C., Honchak B.M., Jung D.O., Karbach L.E.,
RA   Kurdoglu A., Lahiri S., Mastrian S.D., Page L.E., Taylor H.L., Wang Z.T.,
RA   Raymond J., Chen M., Blankenship R.E., Touchman J.W.;
RT   "The genome of Heliobacterium modesticaldum, a phototrophic representative
RT   of the Firmicutes containing the simplest photosynthetic apparatus.";
RL   J. Bacteriol. 190:4687-4696(2008).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=L-arginine + H(+) = agmatine + CO2; Xref=Rhea:RHEA:17641,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:16526, ChEBI:CHEBI:32682,
CC         ChEBI:CHEBI:58145; EC=4.1.1.19;
CC         Evidence={ECO:0000256|ARBA:ARBA00049309};
CC   -!- COFACTOR:
CC       Name=pyruvate; Xref=ChEBI:CHEBI:15361;
CC         Evidence={ECO:0000256|ARBA:ARBA00001928};
CC   -!- SIMILARITY: Belongs to the pyruvoyl-dependent arginine decarboxylase
CC       family. {ECO:0000256|ARBA:ARBA00008611}.
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DR   EMBL; CP000930; ABZ84327.1; -; Genomic_DNA.
DR   AlphaFoldDB; B0TES5; -.
DR   STRING; 498761.HM1_1757; -.
DR   KEGG; hmo:HM1_1757; -.
DR   eggNOG; COG1945; Bacteria.
DR   HOGENOM; CLU_114389_2_0_9; -.
DR   Proteomes; UP000008550; Chromosome.
DR   GO; GO:0008792; F:arginine decarboxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006527; P:L-arginine catabolic process; IEA:InterPro.
DR   Gene3D; 3.30.60.30; -; 1.
DR   Gene3D; 3.50.20.10; Pyruvoyl-Dependent Histidine Decarboxylase, subunit B; 1.
DR   HAMAP; MF_01404; PvlArgDC; 1.
DR   InterPro; IPR016104; Pyr-dep_his/arg-deCO2ase.
DR   InterPro; IPR016105; Pyr-dep_his/arg-deCO2ase_sand.
DR   InterPro; IPR002724; Pyruvoyl-dep_arg_deCO2ase.
DR   NCBIfam; TIGR00286; pyruvoyl-dependent arginine decarboxylase; 1.
DR   PANTHER; PTHR40438; PYRUVOYL-DEPENDENT ARGININE DECARBOXYLASE; 1.
DR   PANTHER; PTHR40438:SF1; PYRUVOYL-DEPENDENT ARGININE DECARBOXYLASE; 1.
DR   Pfam; PF01862; PvlArgDC; 1.
DR   PIRSF; PIRSF005216; Pyruvoyl-dep_arg_deCO2ase; 1.
DR   SFLD; SFLDF00471; Pyruvoyl-dependent_arginine_de; 1.
DR   SFLD; SFLDG01170; Pyruvoyl-dependent_arginine_de; 1.
DR   SFLD; SFLDS00055; Pyruvoyl-Dependent_Histidine/A; 1.
DR   SUPFAM; SSF56271; Pyruvoyl-dependent histidine and arginine decarboxylases; 1.
PE   3: Inferred from homology;
KW   Decarboxylase {ECO:0000256|ARBA:ARBA00022793};
KW   Lyase {ECO:0000256|ARBA:ARBA00023239};
KW   Pyruvate {ECO:0000256|ARBA:ARBA00023317};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008550}.
SQ   SEQUENCE   154 AA;  16449 MW;  8D12930C780E5E05 CRC64;
     MLMLPVPKKF FITAAAAEGK SKLTAFDNAL LKAGIGNVNL VRVSSILPPE CEYAPDMKIP
     YGALVPTAYG SIVSDIPGET IAAAIAVGVS PDSFGVIMEL TGKFTKEEAE ARITRMVQEA
     FEVRGMELKE IKVQAVDHTV ETIGCAFAAA PLWY
//