ID   B0BEZ2_BRAFL            Unreviewed;       377 AA.
AC   B0BEZ2;
DT   26-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   26-FEB-2008, sequence version 1.
DT   10-JUN-2026, entry version 53.
DE   SubName: Full=Putative alpha-2,8-sialyltransferase {ECO:0000313|EMBL:CAP16256.1};
DE   Flags: Fragment;
GN   Name=siat8c {ECO:0000313|EMBL:CAP16256.1};
OS   Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC   Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC   Branchiostomatidae; Branchiostoma.
OX   NCBI_TaxID=7739 {ECO:0000313|EMBL:CAP16256.1};
RN   [1] {ECO:0000313|EMBL:CAP16256.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Bfl-17 {ECO:0000313|EMBL:CAP16256.1};
RX   PubMed=18811928; DOI=10.1186/1471-2148-8-258;
RA   Harduin-Lepers A., Petit D., Mollicone R., Delannoy P., Petit J.M.,
RA   Oriol R.;
RT   "Evolutionary history of the alpha2,8-sialyltransferase (ST8Sia) gene
RT   family: tandem duplications in early deuterostomes explain most of the
RT   diversity found in the vertebrate ST8Sia genes.";
RL   BMC Evol. Biol. 8:258-258(2008).
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC       {ECO:0000256|ARBA:ARBA00004323}; Single-pass type II membrane protein
CC       {ECO:0000256|ARBA:ARBA00004323}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 29 family.
CC       {ECO:0000256|ARBA:ARBA00006003}.
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DR   EMBL; AM901543; CAP16256.1; -; mRNA.
DR   AlphaFoldDB; B0BEZ2; -.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008373; F:sialyltransferase activity; IEA:InterPro.
DR   GO; GO:0009101; P:glycoprotein biosynthetic process; IEA:InterPro.
DR   CDD; cd23970; GT29_ST8SIA3_oligo; 1.
DR   FunFam; 3.90.1480.20:FF:000001; ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2; 1.
DR   Gene3D; 3.90.1480.20; Glycosyl transferase family 29; 1.
DR   InterPro; IPR001675; Glyco_trans_29.
DR   InterPro; IPR050943; Glycosyltr_29_Sialyltrsf.
DR   InterPro; IPR038578; GT29-like_sf.
DR   PANTHER; PTHR11987; ALPHA-2,8-SIALYLTRANSFERASE; 1.
DR   PANTHER; PTHR11987:SF36; SIA-ALPHA-2,3-GAL-BETA-1,4-GLCNAC-R:ALPHA 2,8-SIALYLTRANSFERASE; 1.
DR   Pfam; PF00777; Glyco_transf_29; 1.
PE   2: Evidence at transcript level;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676,
KW   ECO:0000313|EMBL:CAP16256.1};
KW   Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Signal-anchor {ECO:0000256|ARBA:ARBA00022968};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:CAP16256.1};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:CAP16256.1"
SQ   SEQUENCE   377 AA;  43659 MW;  98894C0A9F69261E CRC64;
     SDDILTVQSA FNISDFGEDQ GESLVANQNL SMYDGDPFDE TVTSEGLLVT KIPKQPPWAL
     NMTEVAIAKR KGLRKYFNVV KRISLTKKDV QPGTIMHFDQ SPENYVFSIS PMLYDLLPER
     SPLQGMHHRK CAVIGNSGIL LDSGCGNEIN KADFVFRCNF APTQGYEKDV GTKTNFTTFN
     GSILQYRRFK YLATEKERQK FLKFVQALGD AIFWMPVFTY HTNAIPVRIL TDFFWENRNK
     TNVKLAWLGN ALKWINGWYW RVKHQFKAYR LTSGVFMYTV AQAICDEIHL YGFYPFHEDE
     EGQPIPYHYY EPKDVNQTYS KVHKMDAEHL VLRNLHTKGV LKLTTKKCDP QGSWDIDKYE
     KVGPFPYRIP PKIRTNL
//