ID   A9WFP5_CHLAA            Unreviewed;       187 AA.
AC   A9WFP5;
DT   05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   05-FEB-2008, sequence version 1.
DT   28-JAN-2026, entry version 102.
DE   RecName: Full=Transcription termination/antitermination protein NusG {ECO:0000256|HAMAP-Rule:MF_00948, ECO:0000256|NCBIfam:TIGR00922};
GN   Name=nusG {ECO:0000256|HAMAP-Rule:MF_00948};
GN   OrderedLocusNames=Caur_2184 {ECO:0000313|EMBL:ABY35395.1};
OS   Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl).
OC   Bacteria; Bacillati; Chloroflexota; Chloroflexia; Chloroflexales;
OC   Chloroflexineae; Chloroflexaceae; Chloroflexus.
OX   NCBI_TaxID=324602 {ECO:0000313|EMBL:ABY35395.1, ECO:0000313|Proteomes:UP000002008};
RN   [1] {ECO:0000313|Proteomes:UP000002008}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29366 / DSM 635 / J-10-fl
RC   {ECO:0000313|Proteomes:UP000002008};
RX   PubMed=21714912; DOI=10.1186/1471-2164-12-334;
RA   Tang K.H., Barry K., Chertkov O., Dalin E., Han C.S., Hauser L.J.,
RA   Honchak B.M., Karbach L.E., Land M.L., Lapidus A., Larimer F.W.,
RA   Mikhailova N., Pitluck S., Pierson B.K., Blankenship R.E.;
RT   "Complete genome sequence of the filamentous anoxygenic phototrophic
RT   bacterium Chloroflexus aurantiacus.";
RL   BMC Genomics 12:334-334(2011).
CC   -!- FUNCTION: Participates in transcription elongation, termination and
CC       antitermination. {ECO:0000256|HAMAP-Rule:MF_00948,
CC       ECO:0000256|RuleBase:RU000538}.
CC   -!- SIMILARITY: Belongs to the NusG family. {ECO:0000256|HAMAP-
CC       Rule:MF_00948, ECO:0000256|RuleBase:RU000538}.
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DR   EMBL; CP000909; ABY35395.1; -; Genomic_DNA.
DR   RefSeq; WP_012258049.1; NC_010175.1.
DR   AlphaFoldDB; A9WFP5; -.
DR   FunCoup; A9WFP5; 469.
DR   STRING; 324602.Caur_2184; -.
DR   EnsemblBacteria; ABY35395; ABY35395; Caur_2184.
DR   KEGG; cau:Caur_2184; -.
DR   PATRIC; fig|324602.8.peg.2471; -.
DR   eggNOG; COG0250; Bacteria.
DR   HOGENOM; CLU_067287_1_1_0; -.
DR   InParanoid; A9WFP5; -.
DR   Proteomes; UP000002008; Chromosome.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0006354; P:DNA-templated transcription elongation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006353; P:DNA-templated transcription termination; IEA:UniProtKB-UniRule.
DR   GO; GO:0032784; P:regulation of DNA-templated transcription elongation; IEA:InterPro.
DR   GO; GO:0031564; P:transcription antitermination; IEA:UniProtKB-UniRule.
DR   CDD; cd06091; KOW_NusG; 1.
DR   CDD; cd09891; NGN_Bact_1; 1.
DR   FunFam; 2.30.30.30:FF:000002; Transcription termination/antitermination factor NusG; 1.
DR   FunFam; 3.30.70.940:FF:000002; Transcription termination/antitermination protein NusG; 1.
DR   Gene3D; 2.30.30.30; -; 1.
DR   Gene3D; 3.30.70.940; NusG, N-terminal domain; 1.
DR   HAMAP; MF_00948; NusG; 1.
DR   InterPro; IPR005824; KOW.
DR   InterPro; IPR047050; NGN.
DR   InterPro; IPR006645; NGN-like_dom.
DR   InterPro; IPR036735; NGN_dom_sf.
DR   InterPro; IPR043425; NusG-like.
DR   InterPro; IPR014722; Rib_uL2_dom2.
DR   InterPro; IPR001062; Transcrpt_antiterm_NusG.
DR   InterPro; IPR008991; Translation_prot_SH3-like_sf.
DR   NCBIfam; TIGR00922; nusG; 1.
DR   PANTHER; PTHR30265; RHO-INTERACTING TRANSCRIPTION TERMINATION FACTOR NUSG; 1.
DR   PANTHER; PTHR30265:SF2; TRANSCRIPTION TERMINATION_ANTITERMINATION PROTEIN NUSG; 1.
DR   Pfam; PF00467; KOW; 1.
DR   Pfam; PF02357; NusG; 1.
DR   PRINTS; PR00338; NUSGTNSCPFCT.
DR   SMART; SM00739; KOW; 1.
DR   SMART; SM00738; NGN; 1.
DR   SUPFAM; SSF82679; N-utilization substance G protein NusG, N-terminal domain; 1.
DR   SUPFAM; SSF50104; Translation proteins SH3-like domain; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000002008};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163, ECO:0000256|HAMAP-
KW   Rule:MF_00948};
KW   Transcription antitermination {ECO:0000256|ARBA:ARBA00022814,
KW   ECO:0000256|HAMAP-Rule:MF_00948};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015, ECO:0000256|HAMAP-
KW   Rule:MF_00948};
KW   Transcription termination {ECO:0000256|ARBA:ARBA00022472,
KW   ECO:0000256|HAMAP-Rule:MF_00948}.
FT   DOMAIN          13..121
FT                   /note="NusG-like N-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00738"
FT   DOMAIN          131..158
FT                   /note="KOW"
FT                   /evidence="ECO:0000259|SMART:SM00739"
SQ   SEQUENCE   187 AA;  21773 MW;  9ACE7D96A17BC464 CRC64;
     MSEEKEKEKE ADDRRWYVIH TYSGYENKVK KNLEHRIASM EMQDQIFRVI VPTEEEIEIK
     NGQRRTVNKK IYPGYVLVQM RLTDDSWYVV RNTPGVTSFV GHGNKPTPLD DEEVKAILRQ
     MEGETPKVRV SYQKGQAVKI IDGPFTDFEG IVDAIDHERG RVRVLVSFFG REAPVELDFL
     QVTRLVE
//