ID   A9M586_BRUC2            Unreviewed;       213 AA.
AC   A9M586;
DT   05-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   05-FEB-2008, sequence version 1.
DT   29-APR-2008, entry version 4.
DE   GTP cyclohydrolase I.
GN   Name=folE; ORFNames=BCAN_A1090;
OS   Brucella canis (strain ATCC 23365 / NCTC 10854).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Brucellaceae; Brucella.
OX   NCBI_TaxID=483179;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RA   Setubal J.C., Bowns C., Boyle S., Crasta O.R., Czar M.J.,
RA   Dharmanolla C., Gillespie J.J., Kenyon R.W., Lu J., Mane S.,
RA   Mohapatra S., Nagrani S., Purkayastha A., Rajasimha H.K.,
RA   Shallom J.M., Shallom S., Shukla M., Snyder E.E., Sobral B.W.,
RA   Wattam A.R., Will R., Williams K., Yoo H., Bruce D., Detter C.,
RA   Munk C., Brettin T.S.;
RT   "Brucella canis ATCC 23365 whole genome shotgun sequencing project.";
RL   Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: GTP + H(2)O = formate + 2-amino-4-hydroxy-6-
CC       (erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate.
CC   -!- PATHWAY: Cofactor biosynthesis; tetrahydrofolate biosynthesis; 2-
CC       amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate
CC       from GTP: step 1/5.
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DR   EMBL; CP000872; ABX62141.1; -; Genomic_DNA.
DR   RefSeq; YP_001592912.1; -.
DR   GeneID; 5784077; -.
DR   InterPro; IPR001474; GTP_CycOHase_I.
DR   PANTHER; PTHR11109; GTP_cyclohydro_I; 1.
DR   ProDom; PD003330; GTP_cyclohydroI; 1.
DR   TIGRFAMs; TIGR00063; folE; 1.
PE   4: Predicted;
KW   Hydrolase.
SQ   SEQUENCE   213 AA;  23794 MW;  B43866DF2C208BB5 CRC64;
     MDARILQDND DTSLPVNQAS VTRIHKKPGK AEAEAAVRTL LLWAGEDPDR EGLLETPKRV
     AKAYQELFGG YSESPEEVLG TTFEEVAGYD DMVLVKDISF FSHCEHHMVP IIGKAHVAYL
     PEGRVVGLSK IARVVDIFAR RLQTQESITA QIADSMQRIL KPRGVAVMIE AEHMCMAMRS
     IRKQGSSTIT TTFTGDFKEK ADQQVRFMTL IRT
//