ID A9CJC2_AGRFC Unreviewed; 317 AA. AC A9CJC2; DT 15-JAN-2008, integrated into UniProtKB/TrEMBL. DT 15-JAN-2008, sequence version 1. DT 02-SEP-2026, entry version 93. DE SubName: Full=Agmatinase {ECO:0000313|EMBL:AAK87042.1}; GN Name=speB {ECO:0000313|EMBL:AAK87042.1}; GN OrderedLocusNames=Atu1245 {ECO:0000313|EMBL:AAK87042.1}; OS Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens OS (strain C58)). OC Bacteria; Pseudomonadati; Pseudomonadota; Alphaproteobacteria; OC Hyphomicrobiales; Rhizobiaceae; Rhizobium/Agrobacterium group; OC Agrobacterium; Agrobacterium tumefaciens complex. OX NCBI_TaxID=176299 {ECO:0000313|EMBL:AAK87042.1, ECO:0000313|Proteomes:UP000000813}; RN [1] {ECO:0000313|EMBL:AAK87042.1, ECO:0000313|Proteomes:UP000000813} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C58 / ATCC 33970 {ECO:0000313|Proteomes:UP000000813}; RX PubMed=11743193; DOI=10.1126/science.1066804; RA Wood D.W., Setubal J.C., Kaul R., Monks D.E., Kitajima J.P., Okura V.K., RA Zhou Y., Chen L., Wood G.E., Almeida N.F.Jr., Woo L., Chen Y., RA Paulsen I.T., Eisen J.A., Karp P.D., Bovee D.Sr., Chapman P., RA Clendenning J., Deatherage G., Gillet W., Grant C., Kutyavin T., Levy R., RA Li M.J., McClelland E., Palmieri A., Raymond C., Rouse G., RA Saenphimmachak C., Wu Z., Romero P., Gordon D., Zhang S., Yoo H., Tao Y., RA Biddle P., Jung M., Krespan W., Perry M., Gordon-Kamm B., Liao L., Kim S., RA Hendrick C., Zhao Z.Y., Dolan M., Chumley F., Tingey S.V., Tomb J.F., RA Gordon M.P., Olson M.V., Nester E.W.; RT "The genome of the natural genetic engineer Agrobacterium tumefaciens RT C58."; RL Science 294:2317-2323(2001). RN [2] {ECO:0000313|EMBL:AAK87042.1, ECO:0000313|Proteomes:UP000000813} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C58 / ATCC 33970 {ECO:0000313|Proteomes:UP000000813}; RX PubMed=11743194; DOI=10.1126/science.1066803; RA Goodner B., Hinkle G., Gattung S., Miller N., Blanchard M., Qurollo B., RA Goldman B.S., Cao Y., Askenazi M., Halling C., Mullin L., Houmiel K., RA Gordon J., Vaudin M., Iartchouk O., Epp A., Liu F., Wollam C., Allinger M., RA Doughty D., Scott C., Lappas C., Markelz B., Flanagan C., Crowell C., RA Gurson J., Lomo C., Sear C., Strub G., Cielo C., Slater S.; RT "Genome sequence of the plant pathogen and biotechnology agent RT Agrobacterium tumefaciens C58."; RL Science 294:2323-2328(2001). CC -!- COFACTOR: CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035; CC Evidence={ECO:0000256|PIRSR:PIRSR036979-1}; CC Note=Binds 2 manganese ions per subunit. CC {ECO:0000256|PIRSR:PIRSR036979-1}; CC -!- SIMILARITY: Belongs to the arginase family. Agmatinase subfamily. CC {ECO:0000256|ARBA:ARBA00009227}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AE007869; AAK87042.1; -; Genomic_DNA. DR PIR; A97511; A97511. DR PIR; AH2729; AH2729. DR RefSeq; WP_010971496.1; NC_003062.2. DR AlphaFoldDB; A9CJC2; -. DR STRING; 176299.Atu1245; -. DR EnsemblBacteria; AAK87042; AAK87042; Atu1245. DR GeneID; 1133283; -. DR KEGG; atu:Atu1245; -. DR PATRIC; fig|176299.10.peg.1266; -. DR eggNOG; COG0010; Bacteria. DR HOGENOM; CLU_039478_0_0_5; -. DR OrthoDB; 9788689at2; -. DR PhylomeDB; A9CJC2; -. DR BioCyc; AGRO:ATU1245-MONOMER; -. DR Proteomes; UP000000813; Chromosome circular. DR GO; GO:0008783; F:agmatinase activity; IEA:TreeGrafter. DR GO; GO:0046872; F:metal ion binding; IEA:InterPro. DR CDD; cd11592; Agmatinase_PAH; 1. DR Gene3D; 3.40.800.10; Ureohydrolase domain; 1. DR InterPro; IPR005925; Agmatinase-rel. DR InterPro; IPR006035; Ureohydrolase. DR InterPro; IPR023696; Ureohydrolase_dom_sf. DR InterPro; IPR020855; Ureohydrolase_Mn_BS. DR NCBIfam; TIGR01230; agmatinase; 1. DR NCBIfam; NF002564; PRK02190.1; 1. DR PANTHER; PTHR11358; ARGINASE/AGMATINASE; 1. DR PANTHER; PTHR11358:SF26; GUANIDINO ACID HYDROLASE, MITOCHONDRIAL; 1. DR Pfam; PF00491; Arginase; 1. DR PIRSF; PIRSF036979; Arginase; 1. DR SUPFAM; SSF52768; Arginase/deacetylase; 1. DR PROSITE; PS01053; ARGINASE_1; 1. DR PROSITE; PS51409; ARGINASE_2; 1. PE 3: Inferred from homology; KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU003684}; KW Manganese {ECO:0000256|PIRSR:PIRSR036979-1}; KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, KW ECO:0000256|PIRSR:PIRSR036979-1}; KW Reference proteome {ECO:0000313|Proteomes:UP000000813}. FT BINDING 134 FT /ligand="Mn(2+)" FT /ligand_id="ChEBI:CHEBI:29035" FT /ligand_label="1" FT /evidence="ECO:0000256|PIRSR:PIRSR036979-1" FT BINDING 157 FT /ligand="Mn(2+)" FT /ligand_id="ChEBI:CHEBI:29035" FT /ligand_label="1" FT /evidence="ECO:0000256|PIRSR:PIRSR036979-1" FT BINDING 159 FT /ligand="Mn(2+)" FT /ligand_id="ChEBI:CHEBI:29035" FT /ligand_label="1" FT /evidence="ECO:0000256|PIRSR:PIRSR036979-1" FT BINDING 161 FT /ligand="Mn(2+)" FT /ligand_id="ChEBI:CHEBI:29035" FT /ligand_label="1" FT /evidence="ECO:0000256|PIRSR:PIRSR036979-1" FT BINDING 239 FT /ligand="Mn(2+)" FT /ligand_id="ChEBI:CHEBI:29035" FT /ligand_label="1" FT /evidence="ECO:0000256|PIRSR:PIRSR036979-1" FT BINDING 241 FT /ligand="Mn(2+)" FT /ligand_id="ChEBI:CHEBI:29035" FT /ligand_label="1" FT /evidence="ECO:0000256|PIRSR:PIRSR036979-1" SQ SEQUENCE 317 AA; 34494 MW; D422B02B9E5AD73F CRC64; MPAKTIDHAF TATTLTSAAT DPTHAGVLSF MRRKYTKNLK GVSTAIWGIP FDAATSNRPG ARFGPQAIRR ASAIFDNDPQ YPFARDLFAH MPTIDYGDCL LDYGNHWKTP DTIEKEARRI ISKTDYLLTL GGDHFITWPL LKAHVAKHGR LALVQFDAHQ DTWFDDGKRI DHGSFVARAV RDGLIDPDRS IQIGIRTHAP DDFGIRILHG YEVEDMRASD IASLIVKHTG GMPAYLTFDI DCLDPAFAPG TGTPVAGGPT SAKILSVLRG LGQLDIRGSD VVEVAPAYDH ADITAIAGAT VAMYMLGLRA ERLAKAG //