ID   A8XMS0_CAEBR            Unreviewed;       281 AA.
AC   A8XMS0;
DT   15-JAN-2008, integrated into UniProtKB/TrEMBL.
DT   15-JAN-2008, sequence version 1.
DT   02-SEP-2026, entry version 89.
DE   RecName: Full=Protein FRG1 homolog {ECO:0000256|ARBA:ARBA00072064};
DE   Flags: Fragment;
GN   Name=frg-1 {ECO:0000313|WormBase:CBG15774};
GN   Synonyms=Cbr-frg-1 {ECO:0000313|EMBL:CAP33946.1};
GN   ORFNames=CBG15774 {ECO:0000313|WormBase:CBG15774}, CBG_15774
GN   {ECO:0000313|EMBL:CAP33946.1};
OS   Caenorhabditis briggsae.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6238 {ECO:0000313|EMBL:CAP33946.1, ECO:0000313|Proteomes:UP000008549};
RN   [1] {ECO:0000313|EMBL:CAP33946.1, ECO:0000313|Proteomes:UP000008549}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AF16 {ECO:0000313|EMBL:CAP33946.1,
RC   ECO:0000313|Proteomes:UP000008549};
RX   PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA   Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA   Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA   Fitch D.H., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA   Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA   Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA   Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA   Durbin R., Waterston R.H.;
RT   "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT   genomics.";
RL   PLoS Biol. 1:166-192(2003).
RN   [2] {ECO:0000313|EMBL:CAP33946.1, ECO:0000313|Proteomes:UP000008549}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AF16 {ECO:0000313|EMBL:CAP33946.1,
RC   ECO:0000313|Proteomes:UP000008549};
RA   Ross J.A., Koboldt D.C., Staisch J.E., Chamberlin H.M., Gupta B.P.,
RA   Miller R.D., Baird S.E., Haag E.S.;
RT   "Caenorhabditis briggsae recombinant inbred line genotypes reveal inter-
RT   strain incompatibility and the evolution of recombination.";
RL   PLoS Genet. 7:E1002174-E1002174(2011).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC       Nucleus, Cajal body {ECO:0000256|ARBA:ARBA00004408}. Nucleus, nucleolus
CC       {ECO:0000256|ARBA:ARBA00004604}.
CC   -!- SIMILARITY: Belongs to the FRG1 family.
CC       {ECO:0000256|ARBA:ARBA00010878}.
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DR   EMBL; HE600979; CAP33946.1; -; Genomic_DNA.
DR   RefSeq; XP_002640883.1; XM_002640837.1.
DR   AlphaFoldDB; A8XMS0; -.
DR   FunCoup; A8XMS0; 2378.
DR   STRING; 6238.A8XMS0; -.
DR   GeneID; 8582877; -.
DR   KEGG; cbr:CBG_15774; -.
DR   CTD; 8582877; -.
DR   WormBase; CBG15774; CBP39043; WBGene00035916; Cbr-frg-1.
DR   eggNOG; KOG3962; Eukaryota.
DR   HOGENOM; CLU_094616_0_0_1; -.
DR   InParanoid; A8XMS0; -.
DR   OMA; IEQWEPI; -.
DR   Proteomes; UP000008549; Unassembled WGS sequence.
DR   GO; GO:0015030; C:Cajal body; IEA:UniProtKB-SubCell.
DR   GO; GO:0071013; C:catalytic step 2 spliceosome; IBA:GO_Central.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0055120; C:striated muscle dense body; IBA:GO_Central.
DR   GO; GO:0051015; F:actin filament binding; IBA:GO_Central.
DR   GO; GO:0051017; P:actin filament bundle assembly; IEA:EnsemblMetazoa.
DR   CDD; cd23338; beta-trefoil_FSCN_FRG1; 1.
DR   FunFam; 2.80.10.50:FF:000061; Protein FRG1; 1.
DR   Gene3D; 2.80.10.50; -; 1.
DR   InterPro; IPR008999; Actin-crosslinking.
DR   InterPro; IPR010414; FRG1.
DR   PANTHER; PTHR12928; FRG1 PROTEIN; 1.
DR   PANTHER; PTHR12928:SF0; FSHD REGION GENE 1; 1.
DR   Pfam; PF06229; FRG1; 1.
DR   SUPFAM; SSF50405; Actin-crosslinking proteins; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Myogenesis {ECO:0000256|ARBA:ARBA00022541};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008549};
KW   Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517};
KW   rRNA processing {ECO:0000256|ARBA:ARBA00022552}.
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:CAP33946.1"
SQ   SEQUENCE   281 AA;  31241 MW;  02BA4CE0E436D502 CRC64;
     IFRIFRKMPG GDYNAVKGGG LKLKAGKKNL FKVGKDKKKR NKDEGEKVDP DTVENGGWRK
     IAEYDMKGGI NVAIEVASGE KGFTRTYIAA MDNGKFTIGF PHPEGEGPNP EEIFALVKTP
     DDSKISLKTG FGRYVGVDSE FQLVAFSEAI GVREQFLLVF QDGKTAFQAV ASPLFLSTVA
     SKEGNVHVAS RTATENEMVN IRTDAVKEGP VDWRSAEDRK NARDCETAYV KMYQHSKVDL
     KNRHIAIDVK DRKGVKKAQA EGSAHELLLD RRMKMKSDRY C
//