ID A7UT77_ANOGA Unreviewed; 156 AA. AC A7UT77; DT 23-OCT-2007, integrated into UniProtKB/TrEMBL. DT 23-OCT-2007, sequence version 1. DT 02-SEP-2026, entry version 106. DE RecName: Full=Small ribosomal subunit protein uS4 {ECO:0000256|ARBA:ARBA00035254}; DE AltName: Full=40S ribosomal protein S9 {ECO:0000256|ARBA:ARBA00035410}; GN Name=1274744 {ECO:0000313|EnsemblMetazoa:AGAP005061-PA}; OS Anopheles gambiae (African malaria mosquito). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Altocrustacea; Allotriocarida; OC Hexapoda; Insecta; Pterygota; Neoptera; Eumetabola; Endopterygota; OC Aparaglossata; Panorpida; Diptera; Nematocera; Culicoidea; Culicidae; OC Anophelinae; Anopheles. OX NCBI_TaxID=7165 {ECO:0000313|EnsemblMetazoa:AGAP005061-PA, ECO:0000313|Proteomes:UP000007062}; RN [1] {ECO:0000313|EnsemblMetazoa:AGAP005061-PA, ECO:0000313|Proteomes:UP000007062} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=PEST {ECO:0000313|EnsemblMetazoa:AGAP005061-PA, RC ECO:0000313|Proteomes:UP000007062}; RX PubMed=12364791; DOI=10.1126/science.1076181; RA Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R., RA Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M., Wides R., RA Salzberg S.L., Loftus B., Yandell M., Majoros W.H., Rusch D.B., Lai Z., RA Kraft C.L., Abril J.F., Anthouard V., Arensburger P., Atkinson P.W., RA Baden H., de Berardinis V., Baldwin D., Benes V., Biedler J., Blass C., RA Bolanos R., Boscus D., Barnstead M., Cai S., Center A., Chaturverdi K., RA Christophides G.K., Chrystal M.A., Clamp M., Cravchik A., Curwen V., RA Dana A., Delcher A., Dew I., Evans C.A., Flanigan M., RA Grundschober-Freimoser A., Friedli L., Gu Z., Guan P., Guigo R., RA Hillenmeyer M.E., Hladun S.L., Hogan J.R., Hong Y.S., Hoover J., RA Jaillon O., Ke Z., Kodira C., Kokoza E., Koutsos A., Letunic I., RA Levitsky A., Liang Y., Lin J.J., Lobo N.F., Lopez J.R., Malek J.A., RA McIntosh T.C., Meister S., Miller J., Mobarry C., Mongin E., Murphy S.D., RA O'Brochta D.A., Pfannkoch C., Qi R., Regier M.A., Remington K., Shao H., RA Sharakhova M.V., Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J., RA Thomasova D., Ton L.Q., Topalis P., Tu Z., Unger M.F., Walenz B., Wang A., RA Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M., Yao A., RA Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I., RA Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., Mural R.J., RA Myers E.W., Adams M.D., Smith H.O., Broder S., Gardner M.J., Fraser C.M., RA Birney E., Bork P., Brey P.T., Venter J.C., Weissenbach J., Kafatos F.C., RA Collins F.H., Hoffman S.L.; RT "The genome sequence of the malaria mosquito Anopheles gambiae."; RL Science 298:129-149(2002). RN [2] {ECO:0000313|EnsemblMetazoa:AGAP005061-PA, ECO:0000313|Proteomes:UP000007062} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=PEST {ECO:0000313|EnsemblMetazoa:AGAP005061-PA, RC ECO:0000313|Proteomes:UP000007062}; RX PubMed=14747013; DOI=10.1016/j.pt.2003.11.003; RA Mongin E., Louis C., Holt R.A., Birney E., Collins F.H.; RT "The Anopheles gambiae genome: an update."; RL Trends Parasitol. 20:49-52(2004). RN [3] {ECO:0000313|EnsemblMetazoa:AGAP005061-PA} RP IDENTIFICATION. RC STRAIN=PEST {ECO:0000313|EnsemblMetazoa:AGAP005061-PA}; RG EnsemblMetazoa; RL Submitted (JAN-2021) to UniProtKB. CC -!- FUNCTION: Component of the small ribosomal subunit. The ribosome is a CC large ribonucleoprotein complex responsible for the synthesis of CC proteins in the cell. Part of the small subunit (SSU) processome, first CC precursor of the small eukaryotic ribosomal subunit. During the CC assembly of the SSU processome in the nucleolus, many ribosome CC biogenesis factors, an RNA chaperone and ribosomal proteins associate CC with the nascent pre-rRNA and work in concert to generate RNA folding, CC modifications, rearrangements and cleavage as well as targeted CC degradation of pre-ribosomal RNA by the RNA exosome. CC {ECO:0000256|ARBA:ARBA00045441}. CC -!- SIMILARITY: Belongs to the universal ribosomal protein uS4 family. CC {ECO:0000256|ARBA:ARBA00007465}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AAAB01008900; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR AlphaFoldDB; A7UT77; -. DR EnsemblMetazoa; AGAP005061-RA; AGAP005061-PA; AGAP005061. DR VEuPathDB; VectorBase:AGAMI1_008847; -. DR VEuPathDB; VectorBase:AGAP005061; -. DR HOGENOM; CLU_089738_2_0_1; -. DR Proteomes; UP000007062; Chromosome 2L. DR GO; GO:0015935; C:small ribosomal subunit; IEA:InterPro. DR GO; GO:0019843; F:rRNA binding; IEA:InterPro. DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro. DR GO; GO:0006412; P:translation; IEA:InterPro. DR Gene3D; 3.10.290.10; RNA-binding S4 domain; 1. DR InterPro; IPR022801; Ribosomal_uS4. DR InterPro; IPR018079; Ribosomal_uS4_CS. DR InterPro; IPR005710; Ribosomal_uS4_euk_arc. DR InterPro; IPR001912; Ribosomal_uS4_N. DR InterPro; IPR036986; S4_RNA-bd_sf. DR NCBIfam; NF003139; PRK04051.1; 1. DR NCBIfam; TIGR01018; uS4_arch; 1. DR PANTHER; PTHR11831; 30S 40S RIBOSOMAL PROTEIN; 1. DR PANTHER; PTHR11831:SF5; 40S RIBOSOMAL PROTEIN S9; 1. DR Pfam; PF00163; Ribosomal_S4; 1. DR SMART; SM01390; Ribosomal_S4; 1. DR SUPFAM; SSF55174; Alpha-L RNA-binding motif; 1. DR PROSITE; PS00632; RIBOSOMAL_S4; 1. PE 3: Inferred from homology; KW Reference proteome {ECO:0000313|Proteomes:UP000007062}; KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274}; KW Ribosomal protein {ECO:0000256|ARBA:ARBA00022980}; KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}; KW rRNA-binding {ECO:0000256|ARBA:ARBA00022730}. FT DOMAIN 4..108 FT /note="Small ribosomal subunit protein uS4 N-terminal" FT /evidence="ECO:0000259|SMART:SM01390" SQ SEQUENCE 156 AA; 18462 MW; D0F284BF35E1993B CRC64; MVNHRIPSVF SKTYVTPRRP FEKPRLDAEL KIIGQYGLRN KREVWRVKYT LAKIRKAARE LLTLEEKDEK RLFQGNALLR RLVRIGVLDE SRMKLDYVLG LRIEDFLERR LQTQVFKLGL AKSYHHARVL IRQRHIRSLE RFCAGPVPPQ MIVSAT //