ID   A7RL65_NEMVE            Unreviewed;       359 AA.
AC   A7RL65;
DT   02-OCT-2007, integrated into UniProtKB/TrEMBL.
DT   02-OCT-2007, sequence version 1.
DT   02-SEP-2026, entry version 72.
DE   RecName: Full=Translocation protein SEC62 {ECO:0000256|ARBA:ARBA00021257};
GN   ORFNames=NEMVEDRAFT_v1g159983 {ECO:0000313|EMBL:EDO47877.1};
OS   Nematostella vectensis (Starlet sea anemone).
OC   Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC   Edwardsiidae; Nematostella.
OX   NCBI_TaxID=45351 {ECO:0000313|EMBL:EDO47877.1, ECO:0000313|Proteomes:UP000001593};
RN   [1] {ECO:0000313|EMBL:EDO47877.1, ECO:0000313|Proteomes:UP000001593}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CH2 X CH6 {ECO:0000313|Proteomes:UP000001593};
RX   PubMed=17615350; DOI=10.1126/science.1139158;
RA   Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA   Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA   Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA   Technau U., Martindale M.Q., Rokhsar D.S.;
RT   "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT   genomic organization.";
RL   Science 317:86-94(2007).
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC       {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004477}.
CC   -!- SIMILARITY: Belongs to the SEC62 family.
CC       {ECO:0000256|ARBA:ARBA00010604}.
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DR   EMBL; DS469517; EDO47877.1; -; Genomic_DNA.
DR   AlphaFoldDB; A7RL65; -.
DR   FunCoup; A7RL65; 509.
DR   STRING; 45351.A7RL65; -.
DR   KEGG; nve:5520080; -.
DR   eggNOG; KOG2927; Eukaryota.
DR   HOGENOM; CLU_051910_0_1_1; -.
DR   InParanoid; A7RL65; -.
DR   OMA; YTHEYEG; -.
DR   OrthoDB; 200187at2759; -.
DR   PhylomeDB; A7RL65; -.
DR   Proteomes; UP000001593; Unassembled WGS sequence.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IBA:GO_Central.
DR   GO; GO:0008320; F:transmembrane protein transporter activity; IBA:GO_Central.
DR   GO; GO:0031204; P:post-translational protein targeting to membrane, translocation; IBA:GO_Central.
DR   InterPro; IPR004728; Sec62.
DR   PANTHER; PTHR12443; TRANSLOCATION PROTEIN SEC62; 1.
DR   PANTHER; PTHR12443:SF9; TRANSLOCATION PROTEIN SEC62; 1.
DR   Pfam; PF03839; Sec62; 1.
PE   3: Inferred from homology;
KW   Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001593};
KW   Translocation {ECO:0000256|ARBA:ARBA00023010};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        188..208
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        214..246
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          1..28
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          111..148
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          284..359
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..11
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        287..299
FT                   /note="Gly residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        306..345
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   359 AA;  40820 MW;  5E8208AE6BB7023A CRC64;
     MTEVKRRRKK KESWETDGEE NEPTKEETAV AKHLRWNCPT KSSTMMGNKV EYFMGCKAVD
     CLLDSNWASG KGKTDIIFTT RESCALYLDR LLTKGLFSRV LRIKKKKVDK DKEKAKEKSD
     GEGKKKKEKK EKSEKTEDTK KDSESKTEEG KKKRKVKVKL ELHEEQIFFD ADDEAYVWIY
     DPVHPKTFAM GIVVVIATIA ICMFPLWPTN VREYVWYISV IAAAGIGMIL VLAVLRYIIF
     GILWLISGGR HKFWLLPNLT EECGFLESFV PLYTYEYVAK ETSQGETKGG GEGEPGGTGE
     DQTNTKGDES SEEKESERDS WVKVTDEDVE NAKSEMKEDT VKLQDKAAAI DNGPKTDSE
//