ID   GRCA_CROS8              Reviewed;         127 AA.
AC   A7MH19;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   02-OCT-2007, sequence version 1.
DT   09-APR-2025, entry version 82.
DE   RecName: Full=Autonomous glycyl radical cofactor {ECO:0000255|HAMAP-Rule:MF_00806};
GN   Name=grcA {ECO:0000255|HAMAP-Rule:MF_00806};
GN   OrderedLocusNames=ESA_00681;
OS   Cronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii).
OC   Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
OC   Enterobacterales; Enterobacteriaceae; Cronobacter.
OX   NCBI_TaxID=290339;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-894;
RX   PubMed=20221447; DOI=10.1371/journal.pone.0009556;
RA   Kucerova E., Clifton S.W., Xia X.Q., Long F., Porwollik S., Fulton L.,
RA   Fronick C., Minx P., Kyung K., Warren W., Fulton R., Feng D., Wollam A.,
RA   Shah N., Bhonagiri V., Nash W.E., Hallsworth-Pepin K., Wilson R.K.,
RA   McClelland M., Forsythe S.J.;
RT   "Genome sequence of Cronobacter sakazakii BAA-894 and comparative genomic
RT   hybridization analysis with other Cronobacter species.";
RL   PLoS ONE 5:E9556-E9556(2010).
CC   -!- FUNCTION: Acts as a radical domain for damaged PFL and possibly other
CC       radical proteins. {ECO:0000255|HAMAP-Rule:MF_00806}.
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DR   EMBL; CP000783; ABU75960.1; -; Genomic_DNA.
DR   RefSeq; WP_004387369.1; NC_009778.1.
DR   AlphaFoldDB; A7MH19; -.
DR   SMR; A7MH19; -.
DR   GeneID; 56729571; -.
DR   KEGG; esa:ESA_00681; -.
DR   HOGENOM; CLU_133780_0_0_6; -.
DR   Proteomes; UP000000260; Chromosome.
DR   GO; GO:0005829; C:cytosol; IEA:TreeGrafter.
DR   GO; GO:0008861; F:formate C-acetyltransferase activity; IEA:TreeGrafter.
DR   FunFam; 3.20.70.20:FF:000002; Autonomous glycyl radical cofactor; 1.
DR   Gene3D; 3.20.70.20; -; 1.
DR   HAMAP; MF_00806; GrcA; 1.
DR   InterPro; IPR050244; Auton_GlycylRad_Cofactor.
DR   InterPro; IPR019777; Form_AcTrfase_GR_CS.
DR   InterPro; IPR001150; Gly_radical.
DR   InterPro; IPR011140; Glycyl_radical_cofactor_GrcA.
DR   NCBIfam; TIGR04365; spare_glycyl; 1.
DR   PANTHER; PTHR30191; FORMATE ACETYLTRANSFERASE; 1.
DR   PANTHER; PTHR30191:SF0; FORMATE ACETYLTRANSFERASE 1; 1.
DR   Pfam; PF01228; Gly_radical; 1.
DR   PIRSF; PIRSF000378; Gly_radicl_yfiD; 1.
DR   SUPFAM; SSF51998; PFL-like glycyl radical enzymes; 1.
DR   PROSITE; PS00850; GLY_RADICAL_1; 1.
DR   PROSITE; PS51149; GLY_RADICAL_2; 1.
PE   3: Inferred from homology;
KW   Organic radical; Reference proteome.
FT   CHAIN           1..127
FT                   /note="Autonomous glycyl radical cofactor"
FT                   /id="PRO_1000083722"
FT   DOMAIN          5..127
FT                   /note="Glycine radical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00806"
FT   MOD_RES         102
FT                   /note="Glycine radical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00806"
SQ   SEQUENCE   127 AA;  14433 MW;  4FA5A17B4FBA9C9A CRC64;
     MITGIQITKA ANDSLLNSFW LLDNEKGEAR CVCAKAGFNE DDIVPVSQLG QFEYREIPME
     IKPEVRVEGG QHLNVNVLRR ETLEDAVKHP EKYPQLTIRV SGYAVRFNSL TPEQQRDVIA
     RTFTESL
//