ID   COMB_CLOB1              Reviewed;         239 AA.
AC   A7FPH4;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   11-SEP-2007, sequence version 1.
DT   02-SEP-2026, entry version 86.
DE   RecName: Full=Probable 2-phosphosulfolactate phosphatase {ECO:0000255|HAMAP-Rule:MF_00490};
DE            EC=3.1.3.71 {ECO:0000255|HAMAP-Rule:MF_00490};
GN   Name=comB {ECO:0000255|HAMAP-Rule:MF_00490};
GN   OrderedLocusNames=CLB_3635;
OS   Clostridium botulinum (strain ATCC 19397 / Type A).
OC   Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium; Clostridium botulinum group.
OX   NCBI_TaxID=441770;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 19397 / Type A;
RX   PubMed=18060065; DOI=10.1371/journal.pone.0001271;
RA   Smith T.J., Hill K.K., Foley B.T., Detter J.C., Munk A.C., Bruce D.C.,
RA   Doggett N.A., Smith L.A., Marks J.D., Xie G., Brettin T.S.;
RT   "Analysis of the neurotoxin complex genes in Clostridium botulinum A1-A4
RT   and B1 strains: BoNT/A3, /Ba4 and /B1 clusters are located within
RT   plasmids.";
RL   PLoS ONE 2:E1271-E1271(2007).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(2R)-O-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate +
CC         phosphate; Xref=Rhea:RHEA:23416, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15597, ChEBI:CHEBI:43474, ChEBI:CHEBI:58738; EC=3.1.3.71;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00490};
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000255|HAMAP-
CC         Rule:MF_00490};
CC   -!- SIMILARITY: Belongs to the ComB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00490}.
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DR   EMBL; CP000726; ABS35102.1; -; Genomic_DNA.
DR   RefSeq; WP_012099545.1; NC_009697.1.
DR   AlphaFoldDB; A7FPH4; -.
DR   SMR; A7FPH4; -.
DR   GeneID; 5187232; -.
DR   KEGG; cba:CLB_3635; -.
DR   HOGENOM; CLU_070028_0_0_9; -.
DR   GO; GO:0050532; F:2-phosphosulfolactate phosphatase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0050545; F:sulfopyruvate decarboxylase activity; IEA:TreeGrafter.
DR   FunFam; 3.90.1560.10:FF:000001; Probable 2-phosphosulfolactate phosphatase; 1.
DR   Gene3D; 3.90.1560.10; ComB-like; 1.
DR   HAMAP; MF_00490; ComB; 1.
DR   InterPro; IPR005238; ComB-like.
DR   InterPro; IPR036702; ComB-like_sf.
DR   NCBIfam; NF002052; PRK00886.1-1; 1.
DR   NCBIfam; NF002055; PRK00886.1-4; 1.
DR   PANTHER; PTHR37311; 2-PHOSPHOSULFOLACTATE PHOSPHATASE-RELATED; 1.
DR   PANTHER; PTHR37311:SF1; 2-PHOSPHOSULFOLACTATE PHOSPHATASE-RELATED; 1.
DR   Pfam; PF04029; 2-ph_phosp; 1.
DR   SUPFAM; SSF142823; ComB-like; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Magnesium.
FT   CHAIN           1..239
FT                   /note="Probable 2-phosphosulfolactate phosphatase"
FT                   /id="PRO_1000014460"
SQ   SEQUENCE   239 AA;  26658 MW;  0BF3B8F51CF732B0 CRC64;
     MNIDIVISAD HIDEKGLINK TVIIIDILRA TSVITTAINN GCKKVIPVLT VEEAKDIAKN
     SEEDIILGGE RNALKIDGFN FSNSPLEYTK KYVEGKTVVL STTNGTRAIN NSFNAKTILI
     SALINSKATA KAIDKLHEDL IIINSGTNGQ FSIDDFICSG YLIDCLYNIR KDLELSDIAK
     TAHYIYTNNK DIESFVKKAT HYSRLKSLNL EKDLEYCFQK DIIDVVPQYK DGYIIKSNI
//