ID   A5VLF5_LIMRD            Unreviewed;       372 AA.
AC   A5VLF5;
DT   10-JUL-2007, integrated into UniProtKB/TrEMBL.
DT   10-JUL-2007, sequence version 1.
DT   02-SEP-2026, entry version 77.
DE   SubName: Full=Restriction modification system DNA specificity domain {ECO:0000313|EMBL:ABQ83679.1};
GN   OrderedLocusNames=Lreu_1433 {ECO:0000313|EMBL:ABQ83679.1};
OS   Limosilactobacillus reuteri (strain DSM 20016) (Lactobacillus reuteri).
OC   Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Limosilactobacillus.
OX   NCBI_TaxID=557436 {ECO:0000313|EMBL:ABQ83679.1, ECO:0000313|Proteomes:UP000001991};
RN   [1] {ECO:0000313|Proteomes:UP000001991}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 20016 {ECO:0000313|Proteomes:UP000001991};
RX   PubMed=21379339; DOI=10.1371/journal.pgen.1001314;
RA   Frese S.A., Benson A.K., Tannock G.W., Loach D.M., Kim J., Zhang M.,
RA   Oh P.L., Heng N.C., Patil P.B., Juge N., Mackenzie D.A., Pearson B.M.,
RA   Lapidus A., Dalin E., Tice H., Goltsman E., Land M., Hauser L., Ivanova N.,
RA   Kyrpides N.C., Walter J.;
RT   "The evolution of host specialization in the vertebrate gut symbiont
RT   Lactobacillus reuteri.";
RL   PLoS Genet. 7:E1001314-E1001314(2011).
CC   -!- SIMILARITY: Belongs to the type-I restriction system S methylase
CC       family. {ECO:0000256|ARBA:ARBA00010923}.
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DR   EMBL; CP000705; ABQ83679.1; -; Genomic_DNA.
DR   RefSeq; WP_011953533.1; NC_009513.1.
DR   AlphaFoldDB; A5VLF5; -.
DR   STRING; 557436.Lreu_1433; -.
DR   REBASE; 15569; S1.LreFORF1436P.
DR   KEGG; lre:Lreu_1433; -.
DR   PATRIC; fig|557436.4.peg.1447; -.
DR   eggNOG; COG0732; Bacteria.
DR   HOGENOM; CLU_021095_10_1_9; -.
DR   OMA; NIENEGG; -.
DR   Proteomes; UP000001991; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   Gene3D; 3.90.220.20; DNA methylase specificity domains; 2.
DR   InterPro; IPR000055; Restrct_endonuc_typeI_TRD.
DR   InterPro; IPR044946; Restrct_endonuc_typeI_TRD_sf.
DR   InterPro; IPR052021; Type-I_RS_S_subunit.
DR   PANTHER; PTHR30408:SF12; TYPE I RESTRICTION ENZYME MJAVIII SPECIFICITY SUBUNIT; 1.
DR   PANTHER; PTHR30408; TYPE-1 RESTRICTION ENZYME ECOKI SPECIFICITY PROTEIN; 1.
DR   Pfam; PF01420; Methylase_S; 2.
DR   SUPFAM; SSF116734; DNA methylase specificity domain; 2.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001991};
KW   Restriction system {ECO:0000256|ARBA:ARBA00022747}.
FT   DOMAIN          13..149
FT                   /note="Type I restriction modification DNA specificity"
FT                   /evidence="ECO:0000259|Pfam:PF01420"
FT   DOMAIN          174..349
FT                   /note="Type I restriction modification DNA specificity"
FT                   /evidence="ECO:0000259|Pfam:PF01420"
SQ   SEQUENCE   372 AA;  42455 MW;  FAEE2CBBA5970FC1 CRC64;
     MEYKKFTALF TDVTKTGTKI PKDEYLTTGK NIIIDQGKDS IAGYTDRQKG IFEEVPVIVF
     GDHTRIVKYI DKPFFLGADG VKVLKSKEKE SNYKYLYYAL KAAHIPNTGY NRHFKWLKQI
     NMNYPDLNEQ KNIVDILDSL TRIIKVRQKE LAFFDKLIKA RFVEMFGDPI SNKKSWKKRL
     LNDLVDKIGS GATPKGGKES YQDHGISFIR SMNVHDGYFN YKDLAYINST QAKQLSNVIV
     QSQDVFINIT GASVARSCIV PDDILPARVN QHVSIIRCKS DVLNPIFINN LFLNDSFKRI
     LLSIGLSGGA TRQAITKKQL EMLKIILPPI SLQNEYANFV HQVDKSKFEN IVYLNKTLLN
     KILSQIGDVI RD
//