ID   A4YFS6_METS5            Unreviewed;       191 AA.
AC   A4YFS6;
DT   29-MAY-2007, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2007, sequence version 1.
DT   05-FEB-2025, entry version 74.
DE   SubName: Full=Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit {ECO:0000313|EMBL:ABP95278.1};
GN   OrderedLocusNames=Msed_1115 {ECO:0000313|EMBL:ABP95278.1};
OS   Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509
OS   / TH2).
OC   Archaea; Thermoproteota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Metallosphaera.
OX   NCBI_TaxID=399549 {ECO:0000313|EMBL:ABP95278.1, ECO:0000313|Proteomes:UP000000242};
RN   [1] {ECO:0000313|EMBL:ABP95278.1, ECO:0000313|Proteomes:UP000000242}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2
RC   {ECO:0000313|Proteomes:UP000000242};
RX   PubMed=18083856; DOI=10.1128/AEM.02019-07;
RA   Auernik K.S., Maezato Y., Blum P.H., Kelly R.M.;
RT   "The genome sequence of the metal-mobilizing, extremely thermoacidophilic
RT   archaeon Metallosphaera sedula provides insights into bioleaching-
RT   associated metabolism.";
RL   Appl. Environ. Microbiol. 74:682-692(2008).
CC   -!- SIMILARITY: Belongs to the class-I fumarase family.
CC       {ECO:0000256|ARBA:ARBA00008876}.
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DR   EMBL; CP000682; ABP95278.1; -; Genomic_DNA.
DR   RefSeq; WP_012021065.1; NC_009440.1.
DR   AlphaFoldDB; A4YFS6; -.
DR   STRING; 399549.Msed_1115; -.
DR   GeneID; 91755588; -.
DR   KEGG; mse:Msed_1115; -.
DR   eggNOG; arCOG04406; Archaea.
DR   HOGENOM; CLU_098588_2_0_2; -.
DR   Proteomes; UP000000242; Chromosome.
DR   GO; GO:0016836; F:hydro-lyase activity; IEA:InterPro.
DR   Gene3D; 3.20.130.10; Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain; 1.
DR   InterPro; IPR004647; Fe-S_hydro-lyase_TtdB-typ_cat.
DR   InterPro; IPR036660; Fe-S_hydroAse_TtdB_cat_sf.
DR   NCBIfam; TIGR00723; ttdB_fumA_fumB; 1.
DR   PANTHER; PTHR43351; L(+)-TARTRATE DEHYDRATASE SUBUNIT BETA; 1.
DR   PANTHER; PTHR43351:SF2; L(+)-TARTRATE DEHYDRATASE SUBUNIT BETA-RELATED; 1.
DR   Pfam; PF05683; Fumerase_C; 1.
DR   SUPFAM; SSF117457; FumA C-terminal domain-like; 1.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000313|EMBL:ABP95278.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000242}.
FT   DOMAIN          4..172
FT                   /note="Fe-S hydro-lyase tartrate dehydratase beta-type
FT                   catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF05683"
SQ   SEQUENCE   191 AA;  21238 MW;  FB7DD67D5716DC7C CRC64;
     MSKLETPLKE DVVQSLRLGE EVYLSGKIYI MRDATLRRIF EQGVAPPVNL KDQVVFFGAP
     SFTKDSNGYT ILSVGVTTSQ RMEKYIPRLL NELGVKGIVG KGELSERMNP EFSRAKSVYL
     LFVGGAAALA TSSIQRVNKV WWEDLRGEAL FEVEVNSLGP AFVAIDAQGG NLLMENREKV
     LRNLNALLKE E
//