ID   A4JBH5_BURVG            Unreviewed;       176 AA.
AC   A4JBH5;
DT   01-MAY-2007, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2007, sequence version 1.
DT   04-NOV-2026, entry version 107.
DE   RecName: Full=Ureidoglycolate lyase {ECO:0000256|HAMAP-Rule:MF_00616};
DE            EC=4.3.2.3 {ECO:0000256|HAMAP-Rule:MF_00616};
DE   AltName: Full=Ureidoglycolatase {ECO:0000256|HAMAP-Rule:MF_00616};
GN   Name=allA {ECO:0000256|HAMAP-Rule:MF_00616};
GN   OrderedLocusNames=Bcep1808_0616 {ECO:0000313|EMBL:ABO53628.1};
OS   Burkholderia vietnamiensis (strain G4 / LMG 22486) (Burkholderia cepacia
OS   (strain R1808)).
OC   Bacteria; Pseudomonadati; Pseudomonadota; Betaproteobacteria;
OC   Burkholderiales; Burkholderiaceae; Burkholderia;
OC   Burkholderia cepacia complex.
OX   NCBI_TaxID=269482 {ECO:0000313|EMBL:ABO53628.1, ECO:0000313|Proteomes:UP000002287};
RN   [1] {ECO:0000313|EMBL:ABO53628.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=G4 {ECO:0000313|EMBL:ABO53628.1};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Tiedje J., Richardson P.;
RT   "Complete sequence of Chromosome1 of Burkholderia vietnamiensis G4.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the catabolism of the allantoin degradation
CC       intermediate (S)-ureidoglycolate, generating urea and glyoxylate.
CC       Involved in the utilization of allantoin as nitrogen source.
CC       {ECO:0000256|HAMAP-Rule:MF_00616}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(S)-ureidoglycolate = urea + glyoxylate; Xref=Rhea:RHEA:11304,
CC         ChEBI:CHEBI:16199, ChEBI:CHEBI:36655, ChEBI:CHEBI:57296; EC=4.3.2.3;
CC         Evidence={ECO:0000256|ARBA:ARBA00047684, ECO:0000256|HAMAP-
CC         Rule:MF_00616};
CC   -!- COFACTOR:
CC       Name=Ni(2+); Xref=ChEBI:CHEBI:49786; Evidence={ECO:0000256|HAMAP-
CC         Rule:MF_00616};
CC   -!- PATHWAY: Nitrogen metabolism; (S)-allantoin degradation.
CC       {ECO:0000256|HAMAP-Rule:MF_00616}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738, ECO:0000256|HAMAP-
CC       Rule:MF_00616}.
CC   -!- SIMILARITY: Belongs to the ureidoglycolate lyase family.
CC       {ECO:0000256|HAMAP-Rule:MF_00616}.
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DR   EMBL; CP000614; ABO53628.1; -; Genomic_DNA.
DR   AlphaFoldDB; A4JBH5; -.
DR   KEGG; bvi:Bcep1808_0616; -.
DR   eggNOG; COG3194; Bacteria.
DR   HOGENOM; CLU_070848_1_0_4; -.
DR   UniPathway; UPA00395; -.
DR   Proteomes; UP000002287; Chromosome 1.
DR   GO; GO:0050385; F:ureidoglycolate lyase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0000256; P:allantoin catabolic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0006145; P:purine nucleobase catabolic process; IEA:UniProtKB-UniRule.
DR   CDD; cd20298; cupin_UAH; 1.
DR   Gene3D; 2.60.120.480; Ureidoglycolate hydrolase; 1.
DR   HAMAP; MF_00616; Ureidogly_lyase; 1.
DR   InterPro; IPR011051; RmlC_Cupin_sf.
DR   InterPro; IPR047233; UAH_cupin.
DR   InterPro; IPR007247; Ureidogly_lyase.
DR   InterPro; IPR023525; Ureidogly_lyase_bac.
DR   InterPro; IPR024060; Ureidoglycolate_lyase_dom_sf.
DR   NCBIfam; NF009932; PRK13395.1; 1.
DR   PANTHER; PTHR21221; UREIDOGLYCOLATE HYDROLASE; 1.
DR   PANTHER; PTHR21221:SF1; UREIDOGLYCOLATE LYASE; 1.
DR   Pfam; PF04115; Ureidogly_lyase; 1.
DR   PIRSF; PIRSF017306; Ureidogly_hydro; 1.
DR   SUPFAM; SSF51182; RmlC-like cupins; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000313|EMBL:ABO53628.1};
KW   Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|HAMAP-Rule:MF_00616};
KW   Purine metabolism {ECO:0000256|ARBA:ARBA00022631, ECO:0000256|HAMAP-
KW   Rule:MF_00616}; Reference proteome {ECO:0000313|Proteomes:UP000002287}.
SQ   SEQUENCE   176 AA;  18690 MW;  199FD2AEF28A2D59 CRC64;
     MSGPRILRAQ PLTRDAFAPF GDVIALEGAR HFPINGGTTE RFHDLATIDV CADGGRPLVS
     VFRAQPRALP VALTLMERHP HGSQAFIPLA AVARYAIVVA PAGEFRPDAM RAFVAEGWQG
     VNYAKGVWHH PLLALDAVSD FVIVDRGGPQ PNCDEIALAD PWVLELGLGP ASAGAA
//