ID   A3DIH2_ACET2            Unreviewed;       327 AA.
AC   A3DIH2;
DT   20-MAR-2007, integrated into UniProtKB/TrEMBL.
DT   20-MAR-2007, sequence version 1.
DT   02-SEP-2026, entry version 75.
DE   SubName: Full=Glycosyltransferase sugar-binding region containing DXD motif {ECO:0000313|EMBL:ABN53751.1};
GN   OrderedLocusNames=Cthe_2550 {ECO:0000313|EMBL:ABN53751.1};
OS   Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC
OS   103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) (Clostridium thermocellum).
OC   Bacteria; Bacillati; Bacillota; Clostridia; Acetivibrionales;
OC   Acetivibrionaceae; Acetivibrio.
OX   NCBI_TaxID=203119 {ECO:0000313|EMBL:ABN53751.1, ECO:0000313|Proteomes:UP000002145};
RN   [1] {ECO:0000313|Proteomes:UP000002145}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 /
RC   NRRL B-4536 / VPI 7372 {ECO:0000313|Proteomes:UP000002145};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Wu J.H.D.,
RA   Newcomb M., Richardson P.;
RT   "Complete sequence of Clostridium thermocellum ATCC 27405.";
RL   Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ABN53751.1, ECO:0000313|Proteomes:UP000002145}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 /
RC   NRRL B-4536 / VPI 7372 {ECO:0000313|Proteomes:UP000002145};
RX   PubMed=24295562; DOI=10.1186/1754-6834-6-179;
RA   Wilson C.M., Rodriguez M.Jr., Johnson C.M., Martin S.L., Chu T.M.,
RA   Wolfinger R.D., Hauser L.J., Land M.L., Klingeman D.M., Syed M.H.,
RA   Ragauskas A.J., Tschaplinski T.J., Mielenz J.R., Brown S.D.;
RT   "Global transcriptome analysis of Clostridium thermocellum ATCC 27405
RT   during growth on dilute acid pretreated Populus and switchgrass.";
RL   Biotechnol. Biofuels 6:179-179(2013).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000568; ABN53751.1; -; Genomic_DNA.
DR   RefSeq; WP_003521052.1; NC_009012.1.
DR   AlphaFoldDB; A3DIH2; -.
DR   SMR; A3DIH2; -.
DR   STRING; 203119.Cthe_2550; -.
DR   GeneID; 35805637; -.
DR   KEGG; cth:Cthe_2550; -.
DR   eggNOG; COG3774; Bacteria.
DR   HOGENOM; CLU_073547_2_0_9; -.
DR   OrthoDB; 9802987at2; -.
DR   Proteomes; UP000002145; Chromosome.
DR   GO; GO:0000030; F:mannosyltransferase activity; IEA:TreeGrafter.
DR   GO; GO:0051999; P:mannosyl-inositol phosphorylceramide biosynthetic process; IEA:TreeGrafter.
DR   Gene3D; 3.90.550.20; -; 1.
DR   InterPro; IPR051706; Glycosyltransferase_domain.
DR   InterPro; IPR007577; GlycoTrfase_DXD_sugar-bd_CS.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   PANTHER; PTHR32385:SF15; INOSITOL PHOSPHOCERAMIDE MANNOSYLTRANSFERASE 1; 1.
DR   PANTHER; PTHR32385; MANNOSYL PHOSPHORYLINOSITOL CERAMIDE SYNTHASE; 1.
DR   Pfam; PF04488; Gly_transf_sug; 1.
DR   SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000002145}.
SQ   SEQUENCE   327 AA;  38344 MW;  47248EB29DF8CAAE CRC64;
     MIPKVIHYFW FGRGKKNDVI ERCMDSWKVH LPDYEIKEWN EDNFNVHINN FTLQAYQMKK
     WAFVSDYARL HILYHYGGIY LDTDLEITNS LDPFLDYEGF MGFFSNFDIS GGIIGAAKGN
     KFIKKLLTYY ENKNFIDGNG KIDEKTNVEI ITEISKKHFG FVGENQTQQI LDMTIFPKEY
     FTVRDVNVKN YAIHHYNASW LSHEEMNKHL KSYRKYYEFT VKWLDNLINN KIDLTPYKNK
     CIAIFGKGYI GELLVSYLQN NNVPIRQIID TKFANDTYKD IPIVSSDTIS DEVNLIIITP
     IHSFESIYLS LKEKSCADII SIENLLS
//