ID   A3DD20_ACET2            Unreviewed;       191 AA.
AC   A3DD20;
DT   20-MAR-2007, integrated into UniProtKB/TrEMBL.
DT   20-MAR-2007, sequence version 1.
DT   04-NOV-2026, entry version 88.
DE   RecName: Full=Indolepyruvate ferredoxin oxidoreductase subunit beta {ECO:0000256|NCBIfam:TIGR03334};
DE            EC=1.2.7.8 {ECO:0000256|NCBIfam:TIGR03334};
GN   OrderedLocusNames=Cthe_0614 {ECO:0000313|EMBL:ABN51849.1};
OS   Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC
OS   103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) (Clostridium thermocellum).
OC   Bacteria; Bacillati; Bacillota; Clostridia; Acetivibrionales;
OC   Acetivibrionaceae; Acetivibrio.
OX   NCBI_TaxID=203119 {ECO:0000313|EMBL:ABN51849.1, ECO:0000313|Proteomes:UP000002145};
RN   [1] {ECO:0000313|Proteomes:UP000002145}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 /
RC   NRRL B-4536 / VPI 7372 {ECO:0000313|Proteomes:UP000002145};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Wu J.H.D.,
RA   Newcomb M., Richardson P.;
RT   "Complete sequence of Clostridium thermocellum ATCC 27405.";
RL   Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ABN51849.1, ECO:0000313|Proteomes:UP000002145}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 /
RC   NRRL B-4536 / VPI 7372 {ECO:0000313|Proteomes:UP000002145};
RX   PubMed=24295562; DOI=10.1186/1754-6834-6-179;
RA   Wilson C.M., Rodriguez M.Jr., Johnson C.M., Martin S.L., Chu T.M.,
RA   Wolfinger R.D., Hauser L.J., Land M.L., Klingeman D.M., Syed M.H.,
RA   Ragauskas A.J., Tschaplinski T.J., Mielenz J.R., Brown S.D.;
RT   "Global transcriptome analysis of Clostridium thermocellum ATCC 27405
RT   during growth on dilute acid pretreated Populus and switchgrass.";
RL   Biotechnol. Biofuels 6:179-179(2013).
CC   -!- FUNCTION: Catalyzes the ferredoxin-dependent oxidative decarboxylation
CC       of arylpyruvates. {ECO:0000256|ARBA:ARBA00002995}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=indole-3-pyruvate + 2 oxidized [2Fe-2S]-[ferredoxin] + CoA =
CC         (indol-3-yl)acetyl-CoA + 2 reduced [2Fe-2S]-[ferredoxin] + CO2 +
CC         H(+); Xref=Rhea:RHEA:12645, Rhea:RHEA-COMP:10000, Rhea:RHEA-
CC         COMP:10001, ChEBI:CHEBI:15378, ChEBI:CHEBI:16526, ChEBI:CHEBI:17640,
CC         ChEBI:CHEBI:33737, ChEBI:CHEBI:33738, ChEBI:CHEBI:57271,
CC         ChEBI:CHEBI:57287; EC=1.2.7.8;
CC         Evidence={ECO:0000256|ARBA:ARBA00048332};
CC   -!- SUBUNIT: Heterodimer of the IorA and IorB subunits.
CC       {ECO:0000256|ARBA:ARBA00011238}.
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DR   EMBL; CP000568; ABN51849.1; -; Genomic_DNA.
DR   RefSeq; WP_003516525.1; NC_009012.1.
DR   AlphaFoldDB; A3DD20; -.
DR   STRING; 203119.Cthe_0614; -.
DR   GeneID; 35805290; -.
DR   KEGG; cth:Cthe_0614; -.
DR   eggNOG; COG1014; Bacteria.
DR   HOGENOM; CLU_087284_1_1_9; -.
DR   OMA; AATKRYW; -.
DR   OrthoDB; 9789125at2; -.
DR   Proteomes; UP000002145; Chromosome.
DR   GO; GO:0043805; F:indolepyruvate ferredoxin oxidoreductase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.920.10; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
DR   InterPro; IPR017719; Indolepyruvate_Fd_OxRdtase_bsu.
DR   InterPro; IPR052198; IorB_oxidoreductase.
DR   InterPro; IPR019752; Pyrv/ketoisovalerate_OxRed_cat.
DR   InterPro; IPR002869; Pyrv_flavodox_OxRed_cen.
DR   NCBIfam; TIGR03334; IOR_beta; 1.
DR   NCBIfam; NF005322; PRK06853.1-2; 1.
DR   NCBIfam; NF005325; PRK06853.1-5; 1.
DR   PANTHER; PTHR43854; INDOLEPYRUVATE OXIDOREDUCTASE SUBUNIT IORB; 1.
DR   PANTHER; PTHR43854:SF1; INDOLEPYRUVATE OXIDOREDUCTASE SUBUNIT IORB; 1.
DR   Pfam; PF01558; POR; 1.
DR   SUPFAM; SSF53323; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002145}.
FT   DOMAIN          5..189
FT                   /note="Pyruvate/ketoisovalerate oxidoreductase catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF01558"
SQ   SEQUENCE   191 AA;  21283 MW;  3068EA81B8FF019F CRC64;
     MKKCNIMIVG VGGQGTLLAS RIIGNVALKQ NYDVKVSEVH GMSQRGGSVV TYVKIGDKVY
     SPIIEKGEAD IIMAFEMLEA LRWAEYLKED GKLLVNEQKI NPMPVIIGKE KYPENIMQML
     KENYKNVISL DALKIARECK NIKAVNTVLI GLLAKVLEID KEVWIESIKE VVPSKAVDVN
     LKAFEEGYSR G
//