ID   A2RKF2_LACLM            Unreviewed;       664 AA.
AC   A2RKF2;
DT   06-MAR-2007, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2007, sequence version 1.
DT   04-NOV-2026, entry version 88.
DE   SubName: Full=AguA protein {ECO:0000313|EMBL:CAL97762.1};
DE            EC=3.2.1.139 {ECO:0000313|EMBL:CAL97762.1};
GN   Name=aguA {ECO:0000313|EMBL:CAL97762.1};
GN   OrderedLocusNames=llmg_1169 {ECO:0000313|EMBL:CAL97762.1};
OS   Lactococcus lactis subsp. cremoris (strain MG1363).
OC   Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC   Lactococcus; Lactococcus cremoris subsp. cremoris.
OX   NCBI_TaxID=416870 {ECO:0000313|EMBL:CAL97762.1, ECO:0000313|Proteomes:UP000000364};
RN   [1] {ECO:0000313|EMBL:CAL97762.1, ECO:0000313|Proteomes:UP000000364}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MG1363 {ECO:0000313|EMBL:CAL97762.1,
RC   ECO:0000313|Proteomes:UP000000364};
RX   PubMed=17307855; DOI=10.1128/JB.01768-06;
RA   Wegmann U., O'Connell-Motherway M., Zomer A., Buist G., Shearman C.,
RA   Canchaya C., Ventura M., Goesmann A., Gasson M.J., Kuipers O.P.,
RA   van Sinderen D., Kok J.;
RT   "The complete genome sequence of the lactic acid bacterial paradigm
RT   Lactococcus lactis subsp. cremoris MG1363.";
RL   J. Bacteriol. 189:3256-3270(2007).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AM406671; CAL97762.1; -; Genomic_DNA.
DR   RefSeq; WP_011835070.1; NC_009004.1.
DR   AlphaFoldDB; A2RKF2; -.
DR   SMR; A2RKF2; -.
DR   STRING; 416870.llmg_1169; -.
DR   PaxDb; 416870-llmg_1169; -.
DR   KEGG; llm:llmg_1169; -.
DR   eggNOG; COG3661; Bacteria.
DR   HOGENOM; CLU_007125_1_0_9; -.
DR   OMA; AAIFRNW; -.
DR   OrthoDB; 339499at2; -.
DR   Proteomes; UP000000364; Chromosome.
DR   GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR   GO; GO:0046559; F:alpha-glucuronidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0033939; F:xylan alpha-1,2-glucuronosidase activity; IEA:TreeGrafter.
DR   GO; GO:0045493; P:xylan catabolic process; IEA:InterPro.
DR   Gene3D; 3.90.1330.10; Alpha-glucuronidase, C-terminal domain; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR037054; A-glucoronidase_C_sf.
DR   InterPro; IPR017853; GH_hydrolase_sf.
DR   InterPro; IPR011099; Glyco_hydro_67_C.
DR   InterPro; IPR011100; Glyco_hydro_67_cat.
DR   PANTHER; PTHR39207; ALPHA-GLUCURONIDASE A; 1.
DR   PANTHER; PTHR39207:SF1; ALPHA-GLUCURONIDASE A; 1.
DR   Pfam; PF07477; Glyco_hydro_67C; 1.
DR   Pfam; PF07488; Glyco_hydro_67M; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE   4: Predicted;
KW   Glycosidase {ECO:0000313|EMBL:CAL97762.1};
KW   Hydrolase {ECO:0000313|EMBL:CAL97762.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000364}.
FT   DOMAIN          103..436
FT                   /note="Glycosyl hydrolase family 67 catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF07488"
FT   DOMAIN          437..660
FT                   /note="Glycosyl hydrolase family 67 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF07477"
SQ   SEQUENCE   664 AA;  75975 MW;  1F2144C6C7866DCD CRC64;
     MAIDEMWLQF SILKKRLTNE IFYVNLEYED KITIRLRSEI CEWLGCQLTG EKSEATVVLS
     VNSKLDDNLE AYEVKENEII GASSVGLLYG FYAYLRLKLS GANLSEKSAP AQSLRMINHW
     DQVDGTIERG YAGESIFFGR FGSNDNTDTG SFAVKNIGTD IFRNDFTRLK MYARFLASIG
     INAISLNNVN VRGLGTSLIV SPYIEKVGEI SKLFATFGLK TFLAINWAAP KLIGELKTSD
     PLDENVYTWW QQTIDHIYEV IPDFGGFVVK ADSEGEPGPY QYGRNHADGA NMLAKAFEKY
     NGLVIWRTFV YNSQTDWRKR KNDRAKAAYE NFMPLDGDFS DNVILQIKFG PIDFGVREPL
     MPLFGALKKT NQLMEFQITA EYLGHQLDLN YVLPQWLEMI HFDNYGQPKD TIRANSPVAT
     HSGFIAIGNV GMDENWCGNK LSQANFYGFG RMCWNNDLTA TEILQEWIAL TFSEVKAEVQ
     KEIFELLIDS NQTYELYNAP LAVGSMMVPH YHYGPSINGY EYDRWGAYHF SDRNGLGIDR
     TTATGTGFAS LYAPEVAKVF EDKSKTPDEI LLFFHYVEYG HLLHNGKTLI QTIYDQHFEG
     FERVKSYIKS WKSLKGQVDE ATYDNVADRL ERQLEHARNW RDQVNTYFYR MSGIPDDQGR
     EIYR
//