ID   A2AD75_MOUSE            Unreviewed;        96 AA.
AC   A2AD75;
DT   20-FEB-2007, integrated into UniProtKB/TrEMBL.
DT   20-FEB-2007, sequence version 1.
DT   02-SEP-2026, entry version 128.
DE   SubName: Full=Protein kinase C, zeta {ECO:0000313|Ensembl:ENSMUSP00000101249.2};
GN   Name=Prkcz {ECO:0000313|Ensembl:ENSMUSP00000101249.2,
GN   ECO:0000313|MGI:MGI:97602};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000101249.2, ECO:0000313|Proteomes:UP000000589};
RN   [1] {ECO:0000313|Ensembl:ENSMUSP00000101249.2, ECO:0000313|Proteomes:UP000000589}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000101249.2,
RC   ECO:0000313|Proteomes:UP000000589};
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RG   Mouse Genome Sequencing Consortium;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [2] {ECO:0000313|Ensembl:ENSMUSP00000101249.2, ECO:0000313|Proteomes:UP000000589}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000101249.2,
RC   ECO:0000313|Proteomes:UP000000589};
RX   PubMed=21750661;
RA   Church D.M., Schneider V.A., Graves T., Auger K., Cunningham F., Bouk N.,
RA   Chen H.C., Agarwala R., McLaren W.M., Ritchie G.R., Albracht D.,
RA   Kremitzki M., Rock S., Kotkiewicz H., Kremitzki C., Wollam A., Trani L.,
RA   Fulton L., Fulton R., Matthews L., Whitehead S., Chow W., Torrance J.,
RA   Dunn M., Harden G., Threadgold G., Wood J., Collins J., Heath P.,
RA   Griffiths G., Pelan S., Grafham D., Eichler E.E., Weinstock G.,
RA   Mardis E.R., Wilson R.K., Howe K., Flicek P., Hubbard T.;
RT   "Modernizing reference genome assemblies.";
RL   PLoS Biol. 9:e1001091-e1001091(2011).
RN   [3] {ECO:0000313|Ensembl:ENSMUSP00000101249.2}
RP   IDENTIFICATION.
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000101249.2};
RG   Ensembl;
RL   Submitted (JAN-2026) to UniProtKB.
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DR   AlphaFoldDB; A2AD75; -.
DR   SMR; A2AD75; -.
DR   ProteomicsDB; 322414; -.
DR   Antibodypedia; 3869; 875 antibodies from 48 providers.
DR   Ensembl; ENSMUST00000105624.2; ENSMUSP00000101249.2; ENSMUSG00000029053.17.
DR   UCSC; uc008wde.2; mouse.
DR   AGR; MGI:97602; -.
DR   MGI; MGI:97602; Prkcz.
DR   VEuPathDB; HostDB:ENSMUSG00000029053; -.
DR   GeneTree; ENSGT00940000153497; -.
DR   HOGENOM; CLU_172081_0_0_1; -.
DR   Proteomes; UP000000589; Chromosome 4.
DR   Bgee; ENSMUSG00000029053; Expressed in superior frontal gyrus and 178 other cell types or tissues.
DR   ExpressionAtlas; A2AD75; baseline and differential.
DR   CDD; cd06404; PB1_aPKC; 1.
DR   FunFam; 3.10.20.90:FF:000071; Protein kinase C; 1.
DR   Gene3D; 3.10.20.90; Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1; 1.
DR   InterPro; IPR053793; PB1-like.
DR   InterPro; IPR034877; PB1_aPKC.
DR   InterPro; IPR000270; PB1_dom.
DR   Pfam; PF00564; PB1; 1.
DR   SMART; SM00666; PB1; 1.
DR   SUPFAM; SSF54277; CAD & PB1 domains; 1.
DR   PROSITE; PS51745; PB1; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT   DOMAIN          15..96
FT                   /note="PB1"
FT                   /evidence="ECO:0000259|PROSITE:PS51745"
SQ   SEQUENCE   96 AA;  10818 MW;  21EFE1988ED52023 CRC64;
     MPSRTDPKMD RSGGRVRLKA HYGGDILITS VDAMTTFKDL CEEVRDMCGL HQQHPLTLKW
     VDSEGDPCTV SSQMELEEAF RLVCQGRDEV LIIHGE
//