ID   A0PM77_MYCUA            Unreviewed;       190 AA.
AC   A0PM77;
DT   09-JAN-2007, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2007, sequence version 1.
DT   02-SEP-2026, entry version 107.
DE   RecName: Full=Large ribosomal subunit protein uL5 {ECO:0000256|ARBA:ARBA00035245, ECO:0000256|HAMAP-Rule:MF_01333};
GN   Name=rplE {ECO:0000256|HAMAP-Rule:MF_01333,
GN   ECO:0000313|EMBL:ABL03446.1};
GN   OrderedLocusNames=MUL_0806 {ECO:0000313|EMBL:ABL03446.1};
OS   Mycobacterium ulcerans (strain Agy99).
OC   Bacteria; Bacillati; Actinomycetota; Actinomycetes; Mycobacteriales;
OC   Mycobacteriaceae; Mycobacterium; Mycobacterium ulcerans group.
OX   NCBI_TaxID=362242 {ECO:0000313|EMBL:ABL03446.1, ECO:0000313|Proteomes:UP000000765};
RN   [1] {ECO:0000313|EMBL:ABL03446.1, ECO:0000313|Proteomes:UP000000765}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Agy99 {ECO:0000313|EMBL:ABL03446.1,
RC   ECO:0000313|Proteomes:UP000000765};
RX   PubMed=17210928; DOI=10.1101/gr.5942807;
RA   Stinear T.P., Seemann T., Pidot S., Frigui W., Reysset G., Garnier T.,
RA   Meurice G., Simon D., Bouchier C., Ma L., Tichit M., Porter J.L., Ryan J.,
RA   Johnson P.D., Davies J.K., Jenkin G.A., Small P.L., Jones L.M., Tekaia F.,
RA   Laval F., Daffe M., Parkhill J., Cole S.T.;
RT   "Reductive evolution and niche adaptation inferred from the genome of
RT   Mycobacterium ulcerans, the causative agent of Buruli ulcer.";
RL   Genome Res. 17:192-200(2007).
CC   -!- FUNCTION: This is 1 of the proteins that bind and probably mediate the
CC       attachment of the 5S RNA into the large ribosomal subunit, where it
CC       forms part of the central protuberance. In the 70S ribosome it contacts
CC       protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits;
CC       this bridge is implicated in subunit movement. Contacts the P site
CC       tRNA; the 5S rRNA and some of its associated proteins might help
CC       stabilize positioning of ribosome-bound tRNAs. {ECO:0000256|HAMAP-
CC       Rule:MF_01333}.
CC   -!- SUBUNIT: Part of the 50S ribosomal subunit; part of the 5S
CC       rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA.
CC       Forms a bridge to the 30S subunit in the 70S ribosome.
CC       {ECO:0000256|HAMAP-Rule:MF_01333}.
CC   -!- SIMILARITY: Belongs to the universal ribosomal protein uL5 family.
CC       {ECO:0000256|ARBA:ARBA00008553, ECO:0000256|HAMAP-Rule:MF_01333,
CC       ECO:0000256|RuleBase:RU003930}.
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DR   EMBL; CP000325; ABL03446.1; -; Genomic_DNA.
DR   RefSeq; WP_011739071.1; NC_008611.1.
DR   AlphaFoldDB; A0PM77; -.
DR   SMR; A0PM77; -.
DR   KEGG; mul:MUL_0806; -.
DR   eggNOG; COG0094; Bacteria.
DR   HOGENOM; CLU_061015_2_1_11; -.
DR   Proteomes; UP000000765; Chromosome.
DR   GO; GO:0005840; C:ribosome; IEA:InterPro.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR   FunFam; 3.30.1440.10:FF:000001; 50S ribosomal protein L5; 1.
DR   Gene3D; 3.30.1440.10; -; 1.
DR   HAMAP; MF_01333_B; Ribosomal_uL5_B; 1.
DR   InterPro; IPR002132; Ribosomal_uL5.
DR   InterPro; IPR020930; Ribosomal_uL5_bact.
DR   InterPro; IPR031309; Ribosomal_uL5_C.
DR   InterPro; IPR022803; Ribosomal_uL5_dom_sf.
DR   InterPro; IPR031310; Ribosomal_uL5_N.
DR   NCBIfam; NF000585; PRK00010.1; 1.
DR   PANTHER; PTHR11994; 60S RIBOSOMAL PROTEIN L11-RELATED; 1.
DR   Pfam; PF00281; Ribosomal_L5; 1.
DR   Pfam; PF00673; Ribosomal_L5_C; 1.
DR   PIRSF; PIRSF002161; Ribosomal_L5; 1.
DR   SUPFAM; SSF55282; RL5-like; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000000765};
KW   Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274, ECO:0000256|HAMAP-
KW   Rule:MF_01333};
KW   Ribosomal protein {ECO:0000256|ARBA:ARBA00022980, ECO:0000256|HAMAP-
KW   Rule:MF_01333}; RNA-binding {ECO:0000256|HAMAP-Rule:MF_01333};
KW   rRNA-binding {ECO:0000256|HAMAP-Rule:MF_01333};
KW   tRNA-binding {ECO:0000256|HAMAP-Rule:MF_01333}.
FT   DOMAIN          34..90
FT                   /note="Large ribosomal subunit protein uL5 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00281"
FT   DOMAIN          94..187
FT                   /note="Large ribosomal subunit protein uL5 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00673"
SQ   SEQUENCE   190 AA;  21315 MW;  378F50C9C64B04E4 CRC64;
     MSTTDSAVKI PPRLKERYRS EIRDVLHKQF GYGNVMQIPT VTKVVVNMGV GEAARDAKLI
     NGAVSDLALI TGQRPEIRKA RKSIAQFKLR EGMPVGVRAT LRGDRMWEFL DRLTSIALPR
     IRDFRGLSPK QFDGVGNYTF GLAEQPVFHE IDVDKIDRVR GMDINVVTSA TTDEEGRALL
     RALGFPFKEN
//