ID   A0LS92_ACIC1            Unreviewed;       378 AA.
AC   A0LS92;
DT   12-DEC-2006, integrated into UniProtKB/TrEMBL.
DT   12-DEC-2006, sequence version 1.
DT   02-SEP-2026, entry version 69.
DE   SubName: Full=Diguanylate phosphodiesterase {ECO:0000313|EMBL:ABK52302.1};
GN   OrderedLocusNames=Acel_0529 {ECO:0000313|EMBL:ABK52302.1};
OS   Acidothermus cellulolyticus (strain ATCC 43068 / DSM 8971 / 11B).
OC   Bacteria; Bacillati; Actinomycetota; Actinomycetes; Acidothermales;
OC   Acidothermaceae; Acidothermus.
OX   NCBI_TaxID=351607 {ECO:0000313|EMBL:ABK52302.1, ECO:0000313|Proteomes:UP000008221};
RN   [1] {ECO:0000313|EMBL:ABK52302.1, ECO:0000313|Proteomes:UP000008221}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43068 / DSM 8971 / 11B
RC   {ECO:0000313|Proteomes:UP000008221};
RX   PubMed=19270083; DOI=10.1101/gr.084848.108;
RA   Barabote R.D., Xie G., Leu D.H., Normand P., Necsulea A., Daubin V.,
RA   Medigue C., Adney W.S., Xu X.C., Lapidus A., Parales R.E., Detter C.,
RA   Pujic P., Bruce D., Lavire C., Challacombe J.F., Brettin T.S., Berry A.M.;
RT   "Complete genome of the cellulolytic thermophile Acidothermus
RT   cellulolyticus 11B provides insights into its ecophysiological and
RT   evolutionary adaptations.";
RL   Genome Res. 19:1033-1043(2009).
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DR   EMBL; CP000481; ABK52302.1; -; Genomic_DNA.
DR   RefSeq; WP_011719365.1; NC_008578.1.
DR   AlphaFoldDB; A0LS92; -.
DR   STRING; 351607.Acel_0529; -.
DR   KEGG; ace:Acel_0529; -.
DR   eggNOG; COG2200; Bacteria.
DR   HOGENOM; CLU_015702_3_1_11; -.
DR   InParanoid; A0LS92; -.
DR   OrthoDB; 23692at2; -.
DR   Proteomes; UP000008221; Chromosome.
DR   CDD; cd01948; EAL; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR   PANTHER; PTHR33121:SF76; SIGNALING PROTEIN; 1.
DR   Pfam; PF00563; EAL; 1.
DR   SMART; SM00052; EAL; 1.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   PROSITE; PS50883; EAL; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008221}.
FT   DOMAIN          16..260
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
SQ   SEQUENCE   378 AA;  40946 MW;  6F7DA45751FD4F4C CRC64;
     MPTEATRGAV PAEGSIEACA RLLPGLLRDP EQPRLVFQPI VDLDRAVVAG YEALARFAVS
     PPVAPDVWFA AAAAGGLAAE LERRVVRRVL AARSHLPPNC FLTVNVSPQA LTTDDVLDEF
     RHGGDLAGIF VELTEQQHVL DLAATHKALE ELRQHGAMIA MDDAGSGYSG LQRLVALRPE
     LMKIDRSLVS GIDSDEAKKA CVEMLRVLAG RLDAWLLAEG VETPEELRTL VSLEVPLAQG
     FLLGHPVDDW RGLDARTTAR IRVAARELLG SRQLVRLVER VAIRTPEAAE PPGSSDVVVC
     LDGDGRPASL LINSDAGRPR TVPVTLQLPA TTPITEAARQ CLDRPQPYRF DPVLCVHEDG
     TVAGIVHAER IFDFLTRR
//